|Name||ALFRED UID||Locus Symbol||Chromosome||Band Position|
See Sites List
External Resources: GenBank sequence CHLC markers UniSTS Marker Information
References: See References
Locus Description: The highly variable region on the short arm of the first chromosome (D1S8O) was characterized by Kasai and colleagues (1990) [PubMed ID: 2230693] as a restriction length polymorphism detectable by probe pMCT1 18. Sequencing of flanking regions of this 16-nucleotide repeat enabled design of primers by which amplification of fragments in the range of 370-800 base pairs (bp) was possible. The nomenclature of current alleles reflects the number of repeats in amplified fragments. This system is extensively studied in world populations and has proved to be a very useful marker for genetic diversity and forensic applications [PubMed ID: 10885195].
Sites within this locus ordered by their chromosomal position in the 37.3 NCBI build:
| Site Name |
(Navigates to ALFRED
|dbSNP rs# |
(Navigates to dbSNP
- Drmic I, Schanfield MS, Andjelinovic S, Galavotti R, Gojanovic MD, Trabetti E, Marasovic D, Primorac D, Pignatti PF. "Allele Frequency of Six Highly Polymorphic DNA loci in the Croatian Population". Hum. Biol. 70:949-957. (1998) Online citation.
- Kasai K, Nakamura Y, White R. "Amplification of a variable number of tandem repeats (VNTR) locus (pMCT118) by the polymerase chain reaction (PCR) and its application to forensic science". J. Forensic Sci. 35:1196-200. (1990) Online citation.
- Mastana SS, Reddy PH, Das MK, Reddy P, Das K. "Molecular Genetic Diversity in 5 Populations of Madhya Pradesh, India". Hum. Biol. 72:499-510. (2000) Online citation.
- Vallinoto AC, Cayres-Vallinoto IM, Zago MA, Santos SE, Guerreiro JF. "D1S80 Polymorphismin Amerindians from the Amazon Region of Brazil". Hum. Biol. 70:507-516. (1998) Online citation.
© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan