ALFRED: allele frequency database

The ALlele FREquency Database
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.

ALFRED detailed record information

Locus Information

Name	ALFRED UID	Locus Symbol	Chromosome	Band Position
Alu insertion HS4.14	LO000464O	ALU-HS4.14	1

Synonyms:
Sites List: See Sites List
External Resources: GenBank sequence
References: See References
Locus Description: HS4.14 polymorphic Alu element belongs to the young (Ya5/8) subfamily of human-specfic Alu repeats. It is located on chromosome 1. DNA sequence analysis revealed that it has a long 3'-oligo-dA-rich tail (52 nucleotides in length), a low level of random mutation, and was flanked by short precise direct repeats of 14 nucleotides in length.
GAAAGTAGAGTTGA [ALU] (A)₄₁ GAAAGTAGAGTTGA shows the flanking nucleotide sequences of HS4.14. The composition of the 3' oligo (dA) tail is denoted by the appropriate nucleotide in parenthesis followed by the length in subscripts. The nucleotide sequences comprising the flanking direct repeats of each Alu element are in bold.
Sites within this locus ordered by their chromosomal position in the 37.3 NCBI build:

Site Name (Navigates to ALFRED description)	dbSNP rs# (Navigates to dbSNP reference page)	Chr-Position	Status	# Populations typed
HS4.14 Alu insertion		66135721		60

References:
- Arcot SS, DeAngelis MM, Sherry ST, Adamson AW, Lamerdin JE, Deininger PL, Carrano AV, Batzer MA "Identification and characterization of two polymorphic Ya5 Alu repeats". Mutat Res 382:5-11. (1997) Online citation.

- Watkins WS, Ricker CE, Bamshad MJ, Carroll ML, Nguyen SV, Batzer MA, Harpending HC, Rogers AR, Jorde LB. "Patterns of ancestral human diversity: An analysis of Alu-insertion and restriction-site polymorphisms". Am J Hum Genet 68:738-752. (2001) Online citation.

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© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan