ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Locus Information

NameALFRED UIDLocus SymbolChromosomeBand Position
MCM6 minichromosome maintenance deficient 6LO000912MMCM62q21
Synonyms: Mis5 ; P105MCM ; MCG40308 ;
Sites List: See Sites List
External Resources: Entrez Gene Locus Information   OMIM Locus Description   GenBank mRNA Sequence    UniGene   GDB Gene Information   
References: See References
Locus Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (preRC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.
Sites within this locus ordered by their chromosomal position in the 37.3 NCBI build:
Site Name
(Navigates to ALFRED
description)		dbSNP rs#
(Navigates to dbSNP
reference page)		Chr-PositionStatus# Populations
typed
(-13906)C/T   00
D2S3015 STRP   05
(-13907)C/Grs41525747   1363251137
(-13913)C/Trs41456145   1363251194
(-13915)G/Trs41380347   13632512112
rs4988234rs4988234   1363251433
rs4988262rs4988262   13660421050
intron 13 C/T (-13910 ) SNPrs4988235   13660864688
rs56150605rs56150605   1366088442
rs4988232rs4988232   13660967150
rs4988203rs4988203   13661632350
intron 9 G/A ( -22018 ) SNPrs182549   13661675475
rs4988199rs4988199   13661852050
rs4988186rs4988186   13662185850
C__15793430_10rs3087343   13662254341
rs4988177rs4988177   13662296250
C___2140133_10rs3087353   13662371743
E_rs1435577_10rs1435577   13662494741
C__27478863_10rs3769001   13662607841
E__rs191079_10rs191079   13663377141
C__12044582_1_rs1057031   13663396241
E__rs632632_10rs632632   13663821641

References:
- Lee JK, Hurwitz J. "Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures". Proc Natl Acad Sci U S A. 98:54-9. (2001) Online citation.

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© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan