Sample Name: Kuopio & Oulu
Sample UID: SA003333M
Sample Description:This sample consists of Finnish individuals.
Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.
Number of Chromosomes: 1458
Relation to Other Samples:
References:- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E
(APOE) gene: climate, local adaptations and evolutionary
history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.
- Lehtimäki T, Moilanen T, Viikari J, Akerblom HK, Ehnholm C, Rönnemaa T, Marniemi J, Dahlen G, Nikkari T. "Apolipoprotein E phenotypes in Finnish youths: a cross-sectional and 6-year follow-up study". J Lipid Res. 31:487-95.. (1990) Online citation.
Sample Name: Finns
Sample UID: SA001718R
Sample Description:This sample consists of paternally unrelated men from Finland.
Number of Chromosomes: 154
References:- Nadkarni NA, Weale ME, von Schantz M, Thomas MG. "Evolution of a length polymorphism in the human PER3 gene, a component of the circadian system". J Biol Rhythms. 20:490-499. (2005) Online citation.
Sample Name: Finn
Sample UID: SA002100D
Sample Description:This sample consists of unrelated male and female Finns from Finland.
Number of Chromosomes: 170
References:- Goedde HW, Agarwal DP, Fritze G, Meier-Tackmann D, Singh S, Beckmann G, Bhatia K, Chen LZ, Fang B, Lisker R "Distribution of ADH2 and ALDH2 genotypes in different populations". Hum Genet. 88:344-6. (1992) Online citation.
Sample UID: SA002482Q
Sample Description:This sample consists of Finns.
Number of Chromosomes: 380
References:- Stephens JC, Reich DE, Goldstein DB, Shin HD, Smith MW et.al. "Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes". Am J Hum Genet. 62:1507-15. (1998) Online citation.
Sample UID: SA004064O
Sample Description:This sample consists of unrelated Finns.
Number of Chromosomes: 352
References:- Neuvonen AM, Palo JU, Hedman M, Sajantila A. "Discrimination power of Investigator DIPplex loci in Finnish and Somali populations". Forensic Sci Int Genet. (Epub, ahead of print) (2011) Online citation.
Sample UID: SA001974V
Sample Description:This sample consists of healthy Finnish individuals (78 males, mean age 37 years, 91 females, mean age of 36 years).
Number of Chromosomes: 338
References:- Antikainen M, Murtomaki S, Syvanne M, Pahlman R, Tahvanainen E, Jauhiainen M, Frick MH, Ehnholm C. "The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns". J Clin Invest. 98:883-885. (1996) Online citation.
Sample Name: Finnish
Sample UID: SA003113I
Sample Description:This sample consists of Finnish women who were controls for a study involving preeclampsia women.
Number of Chromosomes: 224
References:- Jääskeläinen E, Keski-Nisula L, Toivonen S, Romppanen EL, Helisalmi S, Punnonen K, Heinonen S. "MTHFR C677T polymorphism is not associated with placental abruption or preeclampsia in Finnish women". Hypertens Pregnancy. 25:73-80. (2006) Online citation.
Sample Name: Finland, Helsinki
Sample UID: SA002701K
Sample Description:This sample consists of specimens from newborns in the major maternity hospital in Finland, The Helsinki University hsopital. Sampling were restricted to babies whose parents were both Finns. Specimens consisted of the remainder of umbilical blood. This study was conducted under the auspices of the International Clearinghouse for Birth Defect Monitoring Systems (ICBDMS) and was coordinated through its head office, the International Center on Birth Defects. Local review boards approved the study.In all cases personal identifiers were removed before data were provided to ICBD for epidemiological analysis.
Number of Chromosomes: 1090
References:- Wilcken B, Bamforth F, Li Z, Zhu H, Ritvanen A, Renlund M, Stoll C, Alembik Y, Dott B, Czeizel AE, Gelman-Kohan Z, Scarano G, Bianca S, Ettore G, Tenconi R, Bellato S, Scala I, Mutchinick OM, López MA, de Walle H, Hofstra R, Joutchenko L, Kavteladze L, Bermejo E, Martínez-Frías ML, Gallagher M, Erickson JD, Vollset SE, Mastroiacovo P, Andria G, Botto LD. "Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide". J Med Genet. 40:619-25.. (2003) Online citation.
Sample Name: Finns(fin)
Sample UID: SA004198W
Number of Chromosomes: 142
References:- Pimenoff VN, Laval G, Comas D, Palo JU, Gut I, Cann H, Excoffier L, Sajantila A. "Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates". Pharmacogenet Genomics. 22:846-857. (2012) Online citation.
Sample UID: SA004129Q
Sample Description:This sample consists of controls from anonymous, voluntary, and healthy male
blood donors (18-65 years old)obtained from Blood Center of the Finnish Red Cross in Tampere. The study protocol was accepted by the local ethical committees and written informed consent was obtained from
all study participants.
Number of Chromosomes: 946
References:- Torniainen S, Hedelin M, Autio V, Rasinperä H, Bälter KA, Klint A, Bellocco R, Wiklund F, Stattin P, Ikonen T, Tammela TL, Schleutker J, Grönberg H, Järvelä I. "Lactase persistence, dietary intake of milk, and the risk for prostate cancer in Sweden and Finland". Cancer Epidemiol Biomarkers Prev 16:956-61. (2007) Online citation.
Sample UID: SA003989D
Sample Description:This sample consists of Finns. These samples were collected from the Helsinki metropolitan region including the city of Vantaa. The samples representing different age groups were included.
Number of Chromosomes: 3914
References:- Nurmi MH, Bishop M, Strain L, Brett F, McGuigan C, Hutchison M, Farrell M, Tilvis R, Erkkilä S, Simell O, Knight R, Haltia M. "The normal population distribution of PRNP codon 129 polymorphism". Acta Neurol Scand. 108:374-8. (2003) Online citation.
Sample UID: SA003922Q
Sample Description:This sample consists of randomly selected blood donors to the Finnish Red Cross Blood Transfusion Service and other volunteers who were healthy controls.
Number of Chromosomes: 242
References:- Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Karjalainen A, Vainio H. "The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finnish study population". Carcinogenesis. 14:85-8. (1993) Online citation.
Sample Name: Finland
Sample UID: SA003663S
Sample Description:This sample consists of persons from Northern Finland Birth cohort living in the northernmost provinces of Finland, Oulu and Lapland.
Number of Chromosomes: 10730
References:- Kaakinen M, Läärä E, Pouta A, Hartikainen AL, Laitinen J, Tammelin TH, Herzig KH, Sovio U, Bennett AJ, Peltonen L, McCarthy MI, Elliott P, De Stavola B, Järvelin MR. "Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling". Am J Epidemiol. 172:653-65. (2010) Online citation.
Sample Name: Helsinki
Sample UID: SA003300G
Sample Description:This sample consists of Finns from Helsinki.
Number of Chromosomes: 1230
References:- Ehnholm C, Lukka M, Kuusi T, Nikkilä E, Utermann G. "Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations". J Lipid Res. 27:227-35. (1986) Online citation.
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E
(APOE) gene: climate, local adaptations and evolutionary
history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.
Sample UID: SA000725O
Sample Description:This sample consists of healthy, unrelated men and women from Finland. The majority of the individuals are from two semi-rural communities (Kitee and Tohmajarvi) in North Karelia, Finland.
Number of Chromosomes: 236
References:- Dunning AM, Renges HH, Xu CF, Peacock R, Brasseur R, Laxer G, Tikkanen MJ, Butler R, Saha N, Hamsten A, et al.
"Two amino acid substitutions in apolipoprotein B are in complete allelic association with the antigen group (x/y) polymorphism: evidence for little recombination in the 3' end of the human gene". Am J Hum Genet. 50:208-21. . (1992) Online citation.
- Kuusi T, Ehnholm C, Huttunen JK, Kostiainen E, Pietinen P, Leino U, Uusitalo U, Nikkari T, Iacono JM, Puska P. "Concentration and composition of serum lipoproteins during a low-fat diet at two levels of polyunsaturated fat". J Lipid Res. 26:360-7. (1985) Online citation.
Sample Name: Tampere and Turku
Sample UID: SA003328Q
Number of Chromosomes: 964
Sample Name: Europe_FIN (Finnish from Finland)
Sample UID: SA004049R
Sample Description:This sample is part of the 1000 Genomes Collection.
Number of Chromosomes: 280
References:- Bulbul O, Filoglu G, Altuncul H, Aradas AF, Ruiz Y, Fondevila M, Phillips C, Carracedo A, Kriegel AK, Schneider PM "A SNP multiplex for the simulataneous prediction of biogeographic ancestry and pigmentaion type". Forensic science International:Genetics Supplement Series 3 e500-501. (2011)
- Corriel 1000 genomes collections sample descriptions Online citation.
Sample UID: SA003984Y
Sample Description:This sample consists of healthy, Finnish controls who were part of a case-control study.
Number of Chromosomes: 266
References:- Scholz SW, Xiromerisiou G, Fung HC, Eerola J, Hellström O, Papadimitriou A, Hadjigeorgiou GM, Tienari PJ, Fernandez HH, Mandel R, Okun MS, Gwinn-Hardy K, Singleton AB. "The human prion gene M129V polymorphism is not associated with idiopathic Parkinson's disease in three distinct populations". Neurosci Lett. 395:227-9. (2006) Online citation.
Sample UID: SA003214K
Sample Description:The subjects are from the Finnish population based Health 2000 study. A nationally representative sample (n=6005) of Finland's general adult population aged 30 years and older, participated in a health examination study concerning their psychological and physical well being. This sample includes 653 healthy Finnish subjects who were controls for the Anxiety Disorder Study. This study was approved by the ethics committee of the National Public Health Institute and written informed consent was obtained from all participants.
Number of Chromosomes: 1306
References:- Sipilä T, Kananen L, Greco D, Donner J, Silander K, Terwilliger JD, Auvinen P, Peltonen L, Lönnqvist J, Pirkola S, Partonen T, Hovatta I. "An Association Analysis of Circadian Genes in Anxiety Disorders". Biol Psychiatry. (Epub ahead of print) (2010) Online citation.
Sample UID: SA000018J
Sample Description:Ethnic Finns from several different parts of Finland (not of Swedish origin). Collected by L. Peltonen (National Public Health Institute, Helsinki).
Number of Chromosomes: 72
References:- Chang FM, Kidd JR, Livak KJ, Pakstis AJ, Kidd KK. "The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus". Hum. Genet. 98:91-101. (1996) Online citation.
- Chang FM, Kidd KK "Rapid molecular haplotyping of the first exon of the human dopamine D4 receptor gene by hetroduplex analysis". American Journal of Medical Genetics (Neuropsychiatric Genetics) 74:91-4. (1997) Online citation.
- Kang AM, Palmatier MA, Kidd KK. "Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3)". Biological Psychiatry 46:151-60. (1999) Online citation.
- Kidd KK et al. http://info.med.yale.edu/genetics/kkidd/pops.html
- Kidd KK, Morar B, Castiglione CM, Zhao H, Pakstis AJ, Speed WC, Bonne-Tamir B, Lu RB, Goldman D, Lee C, Nam YS, Grandy DK, Jenkins T, Kidd JR. "A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus". Hum. Genet. 103:211-27. (1998) Online citation.
- Mateu E, Calafell F, Bonne-Tamir B, Kidd JR, Casals T, Kidd KK, Bertranpetit J. "Allele Frequencies in a Worldwide Survey of a CA Repeat in the First Intron of the CFTR Gene". Human Heredity 49:15-20. (1999) Online citation.
- Palmatier MA, Kang AM, Kidd KK. "Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles". Biol. Psychiatry. 46:557-67. (1999) Online citation.
- Tishkoff SA, Dietzsch E, Speed W, Pakstis AJ, Cheung K, Kidd JR, Bonne-Tamir B, Santachiara-Benerecetti AS, Moral P, Watson E, Krings M, Paabo S, Risch N, Jenkins T, Kidd KK. "Global patterns of linkage disequilibrium at the CD4 locus and
modern human origins". Science 271:1380-7. (1996) Online citation.
- Tishkoff SA, Ruano G, Kidd JR, Kidd KK. "Distribution and frequency of a polymorphic Alu insertion at the plasminogen activator locus in humans". Hum. Genet. 97:759-64. (1996) Online citation.
Sample Name: Karelia
Sample UID: SA003334N
Number of Chromosomes: 220
- Tikkanen MJ, Huttunen JK, Ehnholm C, Pietinen P. "Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high fat diet". Arteriosclerosis 10:285-8.. (1990) Online citation.
Sample UID: SA003592T
Number of Chromosomes: 226
References:- Toivonen S, Keski-Nisula L, Romppanen EL, Helisalmi S, Punnonen K, Heinonen S. "Endothelial nitric oxide synthase polymorphism is not associated with placental abruption in Finnish women". Fetal Diagn Ther 20:508-11. (2005) Online citation.
Sample UID: SA000946T
Sample Description:This sample consists of unrelated Finnish individuals from the Department of Immunobiology at the National Public Health Institute, Helsinki, Finland.
Number of Chromosomes: 6774
References:- Rostedt I, Lalu K, Lukka M, Sajantila A. "Genotyping of five short tandem repeat loci via triplex and duplex PCR.
". Forensic Sci Int. 82:217-26. (1996) Online citation.
Sample UID: SA001856U
Sample Description:This sample consists of unrelated individuals from Helsinki, Finland.
Number of Chromosomes: 196
References:- Libert F, Cochaux P, Beckman G, Samson M, Aksenova M, Cao A, Czeizel A, Claustres M, de la Rua C, Ferrari M, Ferrec C, Glover G, Grinde B, Guran S, Kucinskas V, Lavinha J, Mercier B, Ogur G, Peltonen L, Rosatelli C, Schwartz M, Spitsyn V, Timar L, Beckman L, Parmentier M, Vassart G "The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe". Hum Mol Genet. 7:399-406.. (1998) Online citation.
© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.Originally prototyped by Michael Osier with the aid of Kei CheungUpgrades and maintenance since 2002 by Haseena Rajeevan