ALFRED: allele frequency database

The ALlele FREquency Database
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.

ALFRED detailed record information

Polymorphism Information

Name	ALFRED UID	Locus Name	Locus Symbol
TC-942/3D	SI000336M	Lactase	LCT

Fst	Avg Het	# Populations Typed
0.229	0.201	10

Synonyms:
Frequency Display Formats:

Estimated Heterozygosity:

Frequency Download:

External Resources:
References: See References
Polymorphism Description: TC deletion at -942 and -943 bp, i.e. upstream, of the start of transcription of the LCT gene.
Alleles:

Allele Name	Allele Symbol	Description
DD	DD	TC deletion
TC	TC	no deletion

References:
- Hollox EJ, Poulter M, Wang Y, Krause A, Swallow DM. "Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions". Eur J Hum Genet 7:791-800. (1999) Online citation.

- Hollox EJ, Poulter M, Zvarik M, Ferak V, Krause A, Jenkins T, Saha N, Kozlov AI, Swallow DM. "Lactase Haplotype Diversity in the Old World ". Am. J. Hum. Genet. 68:160-172. (2001) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan