ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
Thr26AsnSI000422ILymphotoxin alpha (TNF superfamily, member 1)LTA
FstAvg Het# Populations Typed
0.1040.4354
Synonyms: SNP59-LTA ; rs1041981 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: dbSNP rs# Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  This is a A/C SNP in the coding region of LTA gene. This snp results in nonsynonymous change Threonine(ACC) -> Aspargine(AAC) at aminoacid position 60 of the gene.
Ancestral Allele:  C
Alleles:
Allele NameAllele SymbolDescription
AA5' - atgcatcttgcccacagc AAC ctcaaacctgctgctcac - 3'
CC5' - atgcatcttgcccacagc ACC ctcaaacctgctgctcac - 3'

References:
- Goddard KA, Hopkins PJ, Hall JM, Witte JS. "Linkage Disequilibrium and Allele-Frequency Distributions for 114 Single-Nucleotide Polymorphisms in Five Populations ". Am. J. Hum. Genet. 66:216-234. (2000) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan