ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
B65 Alu insertionSI000701ICysteine and histidine-rich domain (CHORD)-containing, zinc binding protein 1 CHORDC1
FstAvg Het# Populations Typed
0.0850.45888
Synonyms:
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: GenBank sequence Record  GenBank sequence Record  GenBank sequence Record  GenBank sequence Record   Typing Information Record  
References: See References
Polymorphism Description:  This Alu insertion polymorphism is located on chromosome 11, ~6.7 kb downstream of exon 19 of NAALAD2 gene and ~1.76 kb downstream of CHORDC1 exon 11.
AGTTTACTT [ALU] (A)14(TAAA)3(A)5T(A)11 AGTTTACTT shows the flanking nucleotide sequences of B65. The composition of the 3' oligo (dA) tail is denoted by the appropriate nucleotide in parenthesis followed by the length in subscripts. The nucleotide sequences comprising the flanking direct repeats of each Alu element are in bold.
Alleles:
Allele NameAllele SymbolDescription
Alu Deletion-
Alu Insertion+

References:
- Arcot SS, Wang Z, Weber JL, Deininger PL, Batzer MA. "Alu repeats: a source for the genesis of primate microsatellites". Genomics 29:136-44. (1985) Online citation.

- Comas D, Calafell F, Benchemsi N, Helal A, Lefranc G, Stoneking M, Batzer MA, Bertranpetit J, Sajantila A. "Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits". Hum Genet 107:312-9. (2000) Online citation.

- Deininger PL, Sherry ST, Risch G, Donaldson C, Robichaux MB, Soodyall H, Jenkins T, Sheen F-m, Swergold G, Stoneking M, Batzer MA. "Interspersed repeat insertion polymorphisma for studies of human molecular anthropology. In Genomic diversity: Applications in human population genetics (ed. Papiha, Deka, and Chakraborty)". New York: Kluwer Academic/Plenum Publishers 201-212. (1999)

- Nasidze I, Risch GM, Robichaux M, Sherry ST, Batzer MA, Stoneking M. "Alu insertion polymorphisms and the genetic structure of human populations from the Caucasus". Eur J Hum Genet 9:267-72. (2001) Online citation.

- Stoneking M, Fontius JJ, Clifford SL, Soodyall H, Arcot SS, Saha N, Jenkins T, Tahir MA, Deininger PL, Batzer MA. "Alu insertion polymorphisms and human evolution: evidence for a larger population size in Africa ". Genome Res 7:1061-71. (1997) Online citation.

- Watkins WS, Ricker CE, Bamshad MJ, Carroll ML, Nguyen SV, Batzer MA, Harpending HC, Rogers AR, Jorde LB. "Patterns of ancestral human diversity: An analysis of Alu-insertion and restriction-site polymorphisms". Am J Hum Genet 68:738-752. (2001) Online citation.

- Xiao FX, Yang JF, Cassiman JJ, Decorte R "Diversity at eight polymorphic Alu insertion loci in Chinese populations shows evidence for European admixture in an ethnic minority population from northwest China". Hum Biol 74:555-68. (2002) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan