ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
HS4.75 Alu insertionSI000826QAlu insertion HS4.75ALU-HS4.75
FstAvg Het# Populations Typed
0.370.12863
Synonyms:
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources:  Typing Information Record  GenBank sequence Record  
References: See References
Polymorphism Description:  HS4.75 polymorphic Alu element belongs to the young (Ya5) subfamily of human-specific Alu repeats. It is located on chromosome 3. DNA sequence analysis revealed that it has a long 3'-oligo-dA-rich tail (comprised of nucleotids other than A's), a low level of random mutation, and was flanked by short precise direct repeats of 17 nucleotides in length.
AAAAAAAGAATGAGATC [ALU] (A)27G AAAAAAAGAATGAGATC shows the flanking nucleotide sequences of HS4.75. The composition of the 3' oligo (dA) tail is denoted by the appropriate nucleotide in parenthesis followed by the length in subscripts. The nucleotide sequences comprising the flanking direct repeats of each Alu element are in bold.
Alleles:
Allele NameAllele SymbolDescription
Alu Deletion-
Alu Insertion+

References:
- Arcot SS, Adamson AW, Lamerdin JE, Kanagy B, Deininger PL, Carrano AV, Batzer MA. "Alu fossil relics--distribution and insertion polymorphism". Genome Res 6:1084-92. (1996) Online citation.

- Watkins WS, Ricker CE, Bamshad MJ, Carroll ML, Nguyen SV, Batzer MA, Harpending HC, Rogers AR, Jorde LB. "Patterns of ancestral human diversity: An analysis of Alu-insertion and restriction-site polymorphisms". Am J Hum Genet 68:738-752. (2001) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan