ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
Asn119AsnSI001235LFucosyltransferase 2 (secretor status included)FUT2
FstAvg Het# Populations Typed
0.2550.3670
Synonyms: C357T ; rs281377 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: dbSNP rs # Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  This polymorphism is due to single base change C -> T which results in synonymous substitution Asn -> Asn at bp 357 (codon 119) of FUT2 gene.
Alleles:
Allele NameAllele SymbolDescription
CC5'-tggcagaactaccacctg AAC gactggatggaggaggaata-3'
TT5'-tggcagaactaccacctg AAT gactggatggaggaggaata-3'

References:
- Koda Y, Soejima M, Liu Y, Kimura H. "Molecular basis for secretor type alpha(1,2)-fucosyltransferase gene deficiency in a Japanese population: a fusion gene generated by unequal crossover responsible for the enzyme deficiency". Am J Hum Genet. 59:343-350. (1996) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan