ALFRED detailed record information
|Fst||Avg Het||# Populations Typed|
Frequency Display Formats:
References: See References
Polymorphism Description: A polymorphism resulting in a fusion of 3' region of FUT2 with 5' region of nearby pseudogene, without the C357T neutral mutation. The crossover region has been shown to be within a 61 bp stretch corresponding to regions between bases 253 and 313 of the pseudogene and between bases 211 and 271 of FUT2. The mutation leads to a loss of five EcoRI sites along the 38.7 kb span of FUT2 and the pseudogene.
|Allele Name||Allele Symbol||Description|
|Wt||Wt||Wild type non-fused gene|
|fus||fus||Fusion form of FUT2/pseudogene|
- Koda Y, Soejima M, Liu Y, Kimura H. "Molecular basis for secretor type alpha(1,2)-fucosyltransferase gene deficiency in a Japanese population: a fusion gene generated by unequal crossover responsible for the enzyme deficiency". Am J Hum Genet. 59:343-350. (1996) Online citation.
© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan