ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
5-site haplotype (rs5746849,rs740603,rs4646312,rs165722,rs6269)SI013967ACatechol-O-methyltransferaseCOMT
Synonyms:
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: 
References: See References
Polymorphism Description:  The sites in this 5-site haplotype ordered from 5' to 3' are
rs5746849 (A/G SNP) (UID=SI013958A)
rs740603 (A/G SNP) (UID=SI001346O)
rs4646312 (C/T SNP ) (UID=SI001345N)
rs165722 (C/T SNP) (UID=SI001344M)
rs6269 (A/G SNP) (UID=SI001575S)

Allele name and symbols of the individual polymorphic sites are represented as for the corresponding SNPs.
Ancestral Allele:  G-G-T-C-G
Alleles:
Allele NameAllele SymbolDescription
A-A-C-C-GA-A-C-C-G
A-A-C-T-AA-A-C-T-A
A-A-C-T-GA-A-C-T-G
A-A-T-C-A A-A-T-C-A
A-A-T-C-GA-A-T-C-G
A-A-T-T-AA-A-T-T-A
A-A-T-T-GA-A-T-T-G
A-G-C-C-AA-G-C-C-A
A-G-C-C-GA-G-C-C-G
A-G-C-T-AA-G-C-T-A
A-G-T-C-AA-G-T-C-A
A-G-T-C-GA-G-T-C-G
A-G-T-T-AA-G-T-T-A
G-A-C-C-GG-A-C-C-G
G-A-T-C-A G-A-T-C-A
G-A-T-C-GG-A-T-C-G
G-A-T-T-AG-A-T-T-A
G-A-T-T-GG-A-T-T-G
G-G-C-C-AG-G-C-C-A
G-G-C-C-GG-G-C-C-G
G-G-C-T-AG-G-C-T-A
G-G-C-T-GG-G-C-T-G
G-G-T-C-AG-G-T-C-A
G-G-T-C-GG-G-T-C-G
G-G-T-T-A G-G-T-T-A
G-G-T-T-GG-G-T-T-G

References:
- Mukherjee N, Kidd KK, Pakstis AJ, Speed WC, Li H, Tarnok Z, Barta C, Kajuna SLB, Kidd JR "The Complex Global Pattern of genetic variation and linkage disequilibrium at Catechol-O-methyl transferase (COMT)". Molecular Psychiatry 15:216-225. (2010)
Online citation.


© 2014 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan