|Name||ALFRED UID||Locus Symbol||Chromosome||Band Position|
|Hemoglobin, epsilon 1||LO000601H||HBE1||11||p15.5|
See Sites List
External Resources: GenBank sequence OMIM locus description PharmGKB Gene Information Entrez Gene Locus Information Genopedia (HuGE Navigator)
References: See References
Locus Description: One of five beta-like globin genes are found on chromosome 11, occuring near the 5' end of the 45 kb cluster. Anti-sickling properties of HBE both in vitro as well as in vivo suggest that it could be therapeutically beneficial to adults with sickle phenotypes.
Sites within this locus ordered by their chromosomal position in the 37.3 NCBI build:
| Site Name |
(Navigates to ALFRED
|dbSNP rs# |
(Navigates to dbSNP
|HincII site, 5' to HBE1||rs3834466   ||5291563||22|
- He Z, Russell JE. "A human embryonic hemoglobin inhibits Hb S polymerization in vitro and restores a normal phenotype to mouse models of sickle cell disease". Proc Natl Acad Sci 99:10635-10640. (2002) Online citation.
© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan