ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Locus Information

NameALFRED UIDLocus SymbolChromosomeBand Position
WNK lysine deficient protein kinase 1LO003161LWNK112p13.3
Synonyms: KDP ; PHA2C ; PRKWNK1 ; KIAA0344 ;
Sites List: See Sites List
External Resources: GDB Gene Information   Entrez Gene Locus Information   OMIM Locus Description   GenBank Sequence    UniGene   
References: See References
Locus Description: The WNK kinases are a recently discovered family of serine-threonine kinases that have been shown to play an essential role in the regulation of electrolyte homeostasis. The WNK kinases may be able to influence ion homeostasis through its effects on synaptotagmin function.
Sites within this locus ordered by their chromosomal position in the 37.3 NCBI build:
Site Name
(Navigates to ALFRED
description)		dbSNP rs#
(Navigates to dbSNP
reference page)		Chr-PositionStatus# Populations
typed
rs3858703rs3858703   86351751
rs2107612 rs2107612   88832069
rs2107613rs2107613   88842850
rs11064524rs11064524   88990250
rs724709rs724709   89840051
rs10849559rs10849559   91631051
rs10774464rs10774464   92240851
rs11064562rs11064562   94532250
rs2158501rs2158501   94687850
rs10849568rs10849568   95108150
rs6489755rs6489755   96133651
rs2240283rs2240283   96612450
rs2286006rs2286006   96848951
rs12816718rs12816718   96980050
rs2286007rs2286007   97129151
rs7305099rs7305099   97527651
rs12309274rs12309274   97594851
rs10849573rs10849573   98232151
rs4980973rs4980973   98304650
rs9804992rs9804992   98889450
rs16928112rs16928112   98942450
rs956868rs956868   99091251
rs7300444rs7300444   99393050
rs12828016rs12828016   99836551
rs2255390rs2255390   99976250
rs10849582rs10849582   101317650
rs1060499rs1060499   10202661

References:
- Xu BE, Lee BH, Min X, Lenertz L, Heise CJ, Stippec S, Goldsmith EJ, Cobb MH. "WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension.". Cell Res. 15:6-10. (2005) Online citation.

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© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan