ALFRED

The ALlele FREquency Database
A resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.

ALFRED detailed record information

Population Information

Name	ALFRED UID	Primary Language	Language Family
Pima, Arizona	PO000033G	O'ODHAM	Uto-Aztecan

Synonyms:
Geographic Location¹: 34N, 112.5W; 33N, 111W

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: Fighting the Thrifty Gene Record Tepiman family Record Council Indian Nations: Pima Record Rosetta Project: Language Overview Record The Rise and Fall of Native American Farming Record Ethnologue: Language Map Record Salt River Pima Community Record Ethnologue: Language Description Record obesity and diabetes Record Pima Indians Record
References: See references
Population Description: The Pima Alto, also known as the Akimel O'Odham and the "River Pima", are an Amerindian group of about 14,000 individuals currently residing on several reservations along the Salt and Gila rivers in the vicinity of Phoenix, Arizona. A closely related group, the Papago, or Tohono O'Odham, speak a dialect of the same language and live to the south of the Pima, in the vicinity of Tucson. The Pima language is part of the Uto-Aztecan language family and is still widely used among the Pima and their Papago neighbors: there are about 12,000 speakers in both tribes. The Arizona Pima believe their ancestors to be a prehistoric native American group, the Hohokam. This groups farmed the area hundreds of years ago but seem to have disappeared, probably due to flooding. The Pima traditionally lived in small villages, subsisting through irrigation-farming, and a few thousand Pima continue to farm. The majority, however, have adapted to urban life.
References:
- Seymour DJ "Finding history in the archaeological record: the upper Piman settlement of Guevavi ". Kiva 62:245-60. . (1997)

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Arizona Pima

Sample UID: SA000025H

Sample Description:Arizona Pima sample collected by W. Knowler from individuals in the Phoenix, Arizona area.

Number of Chromosomes: 104

Relation to Other Samples:

References:
- Chang FM, Kidd JR, Livak KJ, Pakstis AJ, Kidd KK. "The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus". Hum. Genet. 98:91-101. (1996) Online citation.

- Kang AM, Palmatier MA, Kidd KK. "Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3)". Biological Psychiatry 46:151-60. (1999) Online citation.

- Kidd KK et al. http://info.med.yale.edu/genetics/kkidd/pops.html

- Kidd KK, Morar B, Castiglione CM, Zhao H, Pakstis AJ, Speed WC, Bonne-Tamir B, Lu RB, Goldman D, Lee C, Nam YS, Grandy DK, Jenkins T, Kidd JR. "A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus". Hum. Genet. 103:211-27. (1998) Online citation.

- Knowler WC, Bennet PH, Hamman RF, Miller M. "Diabetes incidence and prevalence in Pima Indians: a 19-fold greater incidence than in Rochester, Minnesota". Am. J. Epidemiology 108:497. (1978) Online citation.

- Palmatier MA, Kang AM, Kidd KK. "Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles". Biol. Psychiatry. 46:557-67. (1999) Online citation.

- Tishkoff SA, Dietzsch E, Speed W, Pakstis AJ, Cheung K, Kidd JR, Bonne-Tamir B, Santachiara-Benerecetti AS, Moral P, Watson E, Krings M, Paabo S, Risch N, Jenkins T, Kidd KK. "Global patterns of linkage disequilibrium at the CD4 locus and modern human origins". Science 271:1380-7. (1996) Online citation.

- Tishkoff SA, Ruano G, Kidd JR, Kidd KK. "Distribution and frequency of a polymorphic Alu insertion at the plasminogen activator locus in humans". Hum. Genet. 97:759-64. (1996) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Pima Indians

Sample UID: SA001068P

Sample Description:This sample consists of nondiabetic Pima Indians. Subjects were selected from participants in a longitudinal study of diabetes conducted among the residents of the Gila River Indian Community in central Arizona, most of whom are are Pima or Tohono O'odham Indians. Individuals living in the community who are at least five years old are invitied to participate in a standardized health examination every two years. This sample draws from the participant group and all subjects gave informed consent.

Number of Chromosomes: 640

Relation to Other Samples:

References:
- Hanson RL, Ehm MG, Pettitt DJ, Prochazka M, Thompson DB, Timberlake D, Foroud T, Kobes S, Baier L, Burns DK, Almasy L, Blangero J, Garvey WT, Bennett PH, Knowler WC. "An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians". Am J Hum Genet. 63:1130-1138. (1998) Online citation.

- Tataranni PA, Baier L, Jenkinson C, Harper I, Del Parigi A, Bogardus C. "A Ser311Cys mutation in the human dopamine receptor D2 gene is associated with reduced energy expenditure". Diabetes 50:901-904. (2001) Online citation.

¹Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

Top

© 2009 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan