ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
RomanianPO000476R

Synonyms:
Geographic Location1:  48.25N, 21.25E; 43.5N, 29.75E  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: 
References: See references
Population Description: Being curated
References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Romanian

Sample UID: SA003851R

Sample Description:This sample consists of healthy Romanian individuals from Bucharest, Romania. This sample was collected at N.Paulescu Institute(Bucharest), between January 2007 and June 2008 by Toma M and Crăciun AM.

Number of Chromosomes: 300

Relation to Other Samples:

References:
- Toma M, Cimponeriu D, Apostol P, Stavarachi M, Cojocaru M, Belusică L, Crăciun AM, Radu I, Gavrilă L. "Lack of association between ACE ID polymorphism and colorectal cancer in Romanian patients". Chirurgia (Bucur) 104:553-6. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Romanian

Sample UID: SA002627R

Sample Description:This sample consists of unrelated Romanian from the Piatra-Neamt and Bacau districts in Romanian Moldova (Dniester-Carpathian region).

Number of Chromosomes: 174

Relation to Other Samples:

References:
- Varzari A, Stephan W, Stepanov V, Raicu F, Cojocaru R, Roschin Y, Glavce C, Dergachev V, Spiridonova M, Schmidt HD, Weiss E. "Population history of the Dniester-Carpathians: evidence from Alu markers.". J Hum Genet. 52:308-316. (2007) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Roman Jews

Sample UID: SA002771R

Sample Description:This sample consists of Roman Jews from Italy.

Number of Chromosomes: 52

Relation to Other Samples:

References:
- Li H & Kidd KK "Low allele frequency of ADH1B*47His in West China and different ADH1B haplotypes in Western Asia from Eastern Asia". Am. J. Med. Genet. 84:92-94. (2009)


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Romanian

Sample UID: SA000971R

Sample Description:This sample consists of unrelated healthy individuals from Romania. Informed consent was obtained from all participants.

Number of Chromosomes: 130

Relation to Other Samples:

References:
- Comas D, Schmid H, Braeuer S, Flaiz C, Busquets A, Calafell F, Bertranpetit J, Scheil HG, Huckenbeck W, Efremovska L, Schmidt H. "Alu insertion polymorphisms in the Balkans and the origins of the Aromuns.". Ann Hum Genet. 68:120-7. (2004) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Bucharest

Sample UID: SA002731N

Sample Description:This sample consists of individuals from Bucharest, Romania who were recruited as part of multi-centre case-control study in 5 centres from 5 central and eastern european countries. The participants were controls for a study on aerodigestive cancers and were interviewed with a structured questionnaire on residential and lifestyle history by the same team of interviewers in each centre.

Number of Chromosomes: 356

Relation to Other Samples:

References:
- Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S et.al. "Multiple ADH genes are associated with upper aerodigestive cancers". Nat Genet. 40:707-9. (2008) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Romanian

Sample UID: SA004037O

Sample Description:This sample consists of healthy Romanians from south-east of Romania. This sample was collected in N. Paulescu Institute (Bucharest)by Toma M and Cimponeriu D.

Number of Chromosomes: 1500

Relation to Other Samples:

References:
- Cimponeriu D, Apostol P, Radu I, Craciun AM, Serafinceanu C, Toma M, Panaite C, Cheta D. "The insulin polymorphism -23Hph increases the risk for type 1 diabetes mellitus in the Romanian population". Genet Mol Biol 33:610-4. (2010) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

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© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan