ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
TaqI SI000166NHomeo box B3HOXB3
FstAvg Het# Populations Typed
0.1010.26928
Synonyms: rs4646992 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources:   Genbank sequence Record   Typing Protocol Record  GenBank sequence Record  dbSNP ss# Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  An A/G SNP in intron 1 of HOXB3 created by the disruption of the ancestral TaqI recognition site, TCGA, to TCAA. The alleles are coded as "1" (site absent) and "2" (site present). With the protocol provided, the site-absent allele gives a 316 bp fragment and the site-present allele gives 200 bp and 116 bp fragments following digestion with TaqI.
Ancestral Allele:  Site Present
Ancestral Allele Determine by: Digestion of PCR Product on primate DNA
Alleles:
Allele NameAllele SymbolDescription
TaqI Site AbsentA5'-ctggggggtgg TC A A aggtggaaaa-3'
TaqI Site PresentG5'-ctggggggtgg TC G A aggtggaaaa-3'

References:
- Ogura T, Castiglione CM, Pakstis AJ, Kidd KK. "Two RFLPs at the HOX2G locus". Nucleic Acids Res. 19:1716. (1991) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan