ALFRED detailed record information
Synonyms: rs1800955 ;
|Fst||Avg Het||# Populations Typed|
Frequency Display Formats:
External Resources: GenBank sequence Record dbSNP ss# Record PharmGKB Variant Information Record
References: See References
Polymorphism Description: This site is located 521 bp upstream of the first codon. The polymorphism consists of a C or T at this position on the coding strand. There is a report that this polymorphism could affect the transcription of the DRD4 gene.
Ancestral Allele: T
Ancestral Allele Determine by: Sequence on primate (Chimpanzee, Gorilla, Orangutan, Rhesus) DNA.
|Allele Name||Allele Symbol||Description|
|BssHII Site Absent||T||5'-ggagcgggcgtggagg G T GCGC acgaggtcg-3'|
|BssHII Site Present||C||5'-ggagcgggcgtggagg G C GCGC acgaggtcg-3'|
- Okuyama Y, Ishiguro H, Arinama T, et al. "Identification of a polymorphism in the promoter region of DRD4 associated with the human novelty seeking personality trait". Mol. Psychiatry 5:64-9. (2000) Online citation.
- Okuyama Y, Ishiguro H, Arinama T, et al. "A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia". Biochem. Biophys. Res. Commun. 258:292-295. (1999) Online citation.
© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan