ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
exon 9 DdeI (A1343G)SI000683RSolute carrier family 6 (neurotransmitter transporter, dopamine), member 3SLC6A3
FstAvg Het# Populations Typed
0.170.28479
Synonyms: rs6347 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: GenBank sequence Record  dbSNP ss# Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  A A/G SNP altering a DdeI restriction site. This polymorphism is located in exon 9 of the gene SLC6A3.
Ancestral Allele:  G
Ancestral Allele Determine by: sequencing of one each of chimp, bonobo, orangutan, and gorilla
Alleles:
Allele NameAllele SymbolDescription
AA5'-cacgctccctctgtc CTC A G cctgggccgtggtc-3'
GG5'-cacgctccctctgtc CTC G G cctgggccgtggtc-3'

References:
- Barr CL, Xu C, Kroft J, Feng Y, Wigg K, Zai G, Tannock R, Schachar R, Malone M, Roberts W, Nothen MM, Grunhage F, Vandenbergh DJ, Uhl G, Sunohara G, King N, Kennedy JL. "Haplotype study of three polymorphisms at the dopamine transporter locus confirm linkage to attention-deficit/hyperactivity disorder". Biol Psychiatry 49:333-9. (2001) Online citation.

- Morino H, Kawarai T, Izumi Y, Kazuta T, Oda M, Komure O, Udaka F, Kameyama M, Nakamura S, Kawakami H. "A single nucleotide polymorphism of dopamine transporter gene is associated with Parkinson's disease". Ann Neurol 47:528-31. (2000) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan