ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
HGVbase_SNP000002593 (5' MaeIII )SI000797XDopamine Receptor D2DRD2
FstAvg Het# Populations Typed
0.080.21278
Synonyms: rs1799978 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: dbSNP ss# Record  GenBank sequence Record  HGVbase SNP information Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  A G/A SNP altering a MaeIII restriction site. This polymorphism is located at 241 base upstream of the start condon of DRD2.
Alleles:
Allele NameAllele SymbolDescription
AA5'-gcctgcaatcacagctt A TTAC tctgggtgtggg-3'
GG5'-gcctgcaatcacagctt G TTAC tctgggtgtggg-3'

References:
- Arinami T, Gao M, Hamaguchi H, Toru M. "A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia". Hum Mol Genet 6:577-82. (1997) Online citation.

- Sawyer SL, Mukherjee N, Pakstis AJ, Feuk L, Kidd JR, Brookes AJ, Kidd KK. "Linkage disequilibrium patterns vary substantially among populations". Eur J Hum Genet 13:677-686. (2005) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan