ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the U. S. National Science Foundation.
ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
C__25625794_10SI014980WCytochrome P450, family 2, subfamily C, polypeptide 8CYP2C8
FstAvg Het# Populations Typed
0.0780.06544
Synonyms: rs11572080 ;
Frequency on Map:    
Frequency Display Formats:     
Estimated Heterozygosity: 
Frequency Download:   
External Resources: dbSNP rs# Record  PharmGKB Variant Information Record  
References: See References
Polymorphism Description:  This is a A/G SNP in the coding region of CYP2C8 gene. This SNP results in non-synonymous substitution Arginine(AGG) -> Lysine(AAG) at aminoacid position 139 of the gene.
Alleles:
Allele NameAllele SymbolDescription
ArgG5'- gaattttgggatggggaag AG G agcattgaggaccgtgttc -3'
LysA5'- gaattttgggatggggaag AA G agcattgaggaccgtgttc -3'

References:
- Speed WC, Kang SP, Tuck DP, Harris LN, Kidd KK. "Global variation in CYP2C8-CYP2C9 functional haplotypes". The Pharmacogenomics Journal 9:283-90. (2009) Online citation.

© 2012 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan