ALFRED: allele frequency database

The ALlele FREquency Database
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.

00ALFRED detailed record information

Population Information

Name	ALFRED UID	Primary Language	Language Family
Jews, Yemenite	PO000085N	ARABIC, JUDEO-YEMENI	Afro-Asiatic

Synonyms:
Geographic Location¹: 12N, 43E; 18N, 53E

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: Ethnologue: Language Description Record
References: See references
Population Description: Jews have lived in Yemen since ancient times; the first recorded mention of the population appears in the 3rd century CE. The Yemenite Jewish community traditionally lived as traders and artisans. The community was fairly large: by the mid-20th century it numbered more than 60,000 individuals. Increased anti-Jewish violence led to large-scale emigration to Israel in the late 1940s; today only a scattered population of a few hundred Jews remains in Yemen.
References:
- Lewis HS. "Yemenite ethnicity in Israel". Jewish Journal of Sociology 26:5-24. (1984)

- Relethford JH. "Evolution of skin color in Yemenite Jews". Current Anthropology 39:150-2. (1998)

- Tills D, Warlow, Mourant AE, Kopec AC, Edholm OG, Garrard G. "The blood groups and other hereditary blood factors of Yemenite and Kurdish Jews". Annals of Human Biology 4:259-74. (1977)

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews

Sample UID: SA000080I

Sample Description:Sample of Yemenite Jews collected by B. Bonne-Tamir as part of the repository of samples on Israeli populations.

Number of Chromosomes: 110

Relation to Other Samples:

References:
- Mateu E, Calafell F, Bonne-Tamir B, Kidd JR, Casals T, Kidd KK, Bertranpetit J. "Allele Frequencies in a Worldwide Survey of a CA Repeat in the First Intron of the CFTR Gene". Human Heredity 49:15-20. (1999) Online citation.

- Tishkoff SA, Goldman A, Calafell F, Speed WC, Deinard AS, Bonne-Tamir B, Kidd JR, Pakstis AJ, Jenkins T, Kidd KK. "A global haplotype analysis of the myotonic dystrophy locus: implications for the evolution of modern humans and for the origin of myotonic dystrophy mutations". Am. J. Hum. Genet. 62:1389-402. (1998) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Jews, Yemen

Sample UID: SA000249P

Sample Description:Ashkenazi Jews from Yemen. This sample was defined according to the birthplace of the individuals parents or grandparents.

Number of Chromosomes: 176

Relation to Other Samples:

References:
- Ciminelli BM, Jodice C, Scozzari R, Corbo RM, Nahum M, Pompei F, Santachiara-Benerecetti SA, Santolamazza C, Morpurgo GP, Modiano G. "Latitude-correlated genetic polymorphisms: selection or gene flow?". Hum. Biol. 72:557-571. (2000) Online citation.

- Domenici R, Spinetti I, Bargagna M et al. " Population genetic studies on Jews. I. The [alpha]2HS serum glycoprotein, a polymorphism strongly correlated with latitude". Gene Geography 4:99-111. (1990) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews, DNA

Sample UID: SA000081J

Sample Description:Sample of Yemenite Jews, collected by B. Bonne-Tamir as part of the repository of samples on Israeli populations. An early sample of DNA only probably overlapping with sample 80.

Number of Chromosomes: 54

Relation to Other Samples: overlapping with sample SA000080I

References:
- Tishkoff SA, Goldman A, Calafell F, Speed WC, Deinard AS, Bonne-Tamir B, Kidd JR, Pakstis AJ, Jenkins T, Kidd KK. "A global haplotype analysis of the myotonic dystrophy locus: implications for the evolution of modern humans and for the origin of myotonic dystrophy mutations". Am. J. Hum. Genet. 62:1389-402. (1998) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews, Unrelated

Sample UID: SA000016H

Sample Description:Collected by B. Bonne-Tamir and K.K. Kidd consisting primarily of unrelated individuals born in Yemen. A subset of SA000080I used routinely in the Kidd Lab.

Number of Chromosomes: 146

Relation to Other Samples: subset of sample SA000080I

References:
- Chang FM, Kidd JR, Livak KJ, Pakstis AJ, Kidd KK. "The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus". Hum. Genet. 98:91-101. (1996) Online citation.

- Kang AM, Palmatier MA, Kidd KK. "Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3)". Biological Psychiatry 46:151-60. (1999) Online citation.

- Kidd JR, Black FL, Weiss KM, Balazs I, Kidd KK. "Studies of three Amerindian populations using nuclear DNA polymorphisms.". Human Biology 63:775. (1991) Online citation.

- Kidd KK et al. http://info.med.yale.edu/genetics/kkidd/pops.html

- Kidd KK, Kidd JR, Bonne-Tamir B, New MI. "Genetic diversity among Jews, Diseases and Markers at the DNA Level". Bonne-Tamir B and Adam A, Eds. (Oxford University Press, Oxford) 33-44. (1992)

- Kidd KK, Morar B, Castiglione CM, Zhao H, Pakstis AJ, Speed WC, Bonne-Tamir B, Lu RB, Goldman D, Lee C, Nam YS, Grandy DK, Jenkins T, Kidd JR. "A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus". Hum. Genet. 103:211-27. (1998) Online citation.

- Palmatier MA, Kang AM, Kidd KK. "Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles". Biol. Psychiatry. 46:557-67. (1999) Online citation.

- Tishkoff SA, Dietzsch E, Speed W, Pakstis AJ, Cheung K, Kidd JR, Bonne-Tamir B, Santachiara-Benerecetti AS, Moral P, Watson E, Krings M, Paabo S, Risch N, Jenkins T, Kidd KK. "Global patterns of linkage disequilibrium at the CD4 locus and modern human origins". Science 271:1380-7. (1996) Online citation.

- Tishkoff SA, Ruano G, Kidd JR, Kidd KK. "Distribution and frequency of a polymorphic Alu insertion at the plasminogen activator locus in humans". Hum. Genet. 97:759-64. (1996) Online citation.

- Zoossmann-Disken A, Ticher A, Hakim I, Goldwitch Z, Rubinstein A, Bonne-Tamir B. "Genetic affinities of Ethiopian Jews. affinities of Ethiopian Jews". Israel J. of Med. Sciences 27:245. (1991) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews

Sample UID: SA003959A

Sample Description:This sample is the subset of the Kidd lab Yemenite Jews sample.

Number of Chromosomes: 50

Relation to Other Samples: Subset of sample SA000016H

References:
- Publication pending

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews, Israel

Sample UID: SA003135M

Sample Description:This sample consists of Yemenite Jews from Israel. This sample was randomly collected from newborns and blood donors at Hadassah University Hospital, Jerusalem. The ethnic origin was determined based on the place of birth of both parents and four grandparents.

Number of Chromosomes: 166

Relation to Other Samples:

References:
- Pollak RD, Friedlander Y, Pollak A, Idelson M, Bejarano-AchacheI, Blumenfeld A "Ethnic differences in the frequency of the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy Israeli populations". Genet Test. 4:309-11. (2000) Online citation.

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jews

Sample UID: SA004370O

Sample Description:This sample is part of KiddLab samples collection and is a subset of SA000016H.

Number of Chromosomes: 74

Relation to Other Samples: Subset of SA000016H

References:
- Kenneth K. Kidd et al. "Data unpublished".

Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Yemenite Jew

Sample UID: SA004704P

Sample Description:This sample consists of Yemenite Jewish individuals from West Asia. Written informed consent was obtained from all individuals. This sample is part of Caixia Li's group in Institute of Forensic Science, Beijing, China. It was provided by the Kenneth K. Kidd's laboratory to Caixia lab.

Number of Chromosomes: 82

Relation to Other Samples:

References:
- Jiang L, Wei YL, Zhao L, Li N, Liu T, Liu HB, Ren LJ, Li JL, Hao HF, Li Q, Li CX. "Global analysis of population stratification using a smart panel of 27 continental ancestry-informative SNPs". Forensic Sci Int Genet. 35:e10-e12. (2018) Online citation.

¹Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

Top

© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan