ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
MoroccansPO000105G

Synonyms:
Geographic Location1:  36N, 14W; 27N, .75W  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: 
References: See references
Population Description: 
References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: South-Central Moroccans

Sample UID: SA000292N

Sample Description:Population sample from Morocco (El Jadida, south Atlantic coast), (58 males and 43 females). The sample was collected on the basis of family history information consisting of people coming from the Abda, Chaouia, Doukkali, and Tadla districts in south-central Morocco. All of the subjects were Arab speakers, however it is likely that most of the people living in this region probably descended from the ancient Maghreb populations .

Number of Chromosomes: 202

Relation to Other Samples:

References:
- Kandil M, Moral P, Esteban E, Autori L, Mameli GE, Zaoui D, Calo C, Luna F, Vacca L, Vona G. "Red cell enzyme polymorphisms in Moroccans and southern Spaniards: new data for the genetic history of the western Mediterranean.". Hum. Biol. 71:791-802. (1999) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Northern Moroccans

Sample UID: SA000110C

Sample Description:Northern Moroccans collected by Drs. J. Bertran-Petit and D. Comas. The sample collected in North Morocco is mainly composed of Berbers from the north part of the country, mainly from the Rif montains.

Number of Chromosomes: 186

Relation to Other Samples:

References:
- Bosch E, Calafell F, Comas D, Oefner PJ, Underhill PA, Bertranpetit J. "High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula.". Am. J. Hum. Genet. 68:1019-29. (2001) Online citation.

- Comas D, Calafell F, Benchemsi N, Helal A, Lefranc G, Stoneking M, Batzer MA, Bertranpetit J, Sajantila A. "Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits". Hum Genet 107:312-9. (2000) Online citation.

- Osier MV, Pakstis AJ, Soodyall H, Comas D, Goldman D, Odunsi A, Okonofua F, Parnas J, Schulz LO, Bertranpetit J, Bonne-Tamir B, Lu RB, Kidd JR, Kidd KK. "A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity". Am J Hum Genet 71:84-99. (2002) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Central Morrocans

Sample UID: SA000111D

Sample Description:Central Morrocans collected by Dr. J. Bertran-Petit and D. Comas. The sample from Central Morocco is composed basically by Arabs from the area near Rabat and Casablanca.

Number of Chromosomes: 174

Relation to Other Samples:

References:
- Bosch E, Calafell F, Comas D, Oefner PJ, Underhill PA, Bertranpetit J. "High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula.". Am. J. Hum. Genet. 68:1019-29. (2001) Online citation.

- Comas D, Calafell F, Benchemsi N, Helal A, Lefranc G, Stoneking M, Batzer MA, Bertranpetit J, Sajantila A. "Alu insertion polymorphisms in NW Africa and the Iberian Peninsula: evidence for a strong genetic boundary through the Gibraltar Straits". Hum Genet 107:312-9. (2000) Online citation.

- Osier MV, Pakstis AJ, Soodyall H, Comas D, Goldman D, Odunsi A, Okonofua F, Parnas J, Schulz LO, Bertranpetit J, Bonne-Tamir B, Lu RB, Kidd JR, Kidd KK. "A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity". Am J Hum Genet 71:84-99. (2002) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccans

Sample UID: SA001337O

Sample Description:This sample consists of healthy, unrelated Moroccans living in Brussels ,Belgium.

Number of Chromosomes: 290

Relation to Other Samples:

References:
- Brinkmann B, Junge A, Meyer E, Wiegand P. "Population genetic diversity in relation to microsatellite heterogeneity". Hum Mutat 11:135-144. (1998) Online citation.

- Rolf B, Waterkamp K, Huhne J. "Allele frequency data for the FGA locus in eight populations". Int J Legal Med. 111:55-6. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccans

Sample UID: SA000864S

Sample Description:This sample consists of healthy unrelated adult Moroccans living in Brussels, Belgium.

Number of Chromosomes: 270

Relation to Other Samples:

References:
- Brinkmann B, Junge A, Meyer E, Wiegand P. "Population genetic diversity in relation to microsatellite heterogeneity". Hum Mutat 11:135-144. (1998) Online citation.

- Takeshita H, Meyer E, Brinkmann B. "The STR loci HumTPO and HumLPL: population genetic data in eight populations". Int J Legal Med. 110:331-3. . (1997) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Casablanca

Sample UID: SA000993V

Sample Description:This sample consists of unrelated healthy residents in Casablanca (the industrial capital of Morocco) where the urban growth is maintained by immigration from all parts of Morocco (the urban residents represent a sample of the population of the whole area from which the immigrants have originated).

Number of Chromosomes: 106

Relation to Other Samples:

References:
- Chbel F, de Pancorbo MM, Martinez-Bouzas C, Azeddoug H, Alvarez-Alvarez M, Rodriguez-Tojo MJ, Nadifi S "Polymorphism of Six Alu Insertions in Morocco: Comparative Study between Arabs, Berbers, and Casablanca Residents". Russian Journal of Genetics 39:1184-1190. (2003) Online citation.


Sample Information:

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Sample Name: Moroccan

Sample UID: SA001739U

Sample Description:This sample consists of unrelated individuals of Moroccan origin living in Belgium.

Number of Chromosomes: 410

Relation to Other Samples:

References:
- Mertens G, Jehaes E, Rand S, Van Brussel K, Jacobs W, Van Marck E. "Population genetic analysis of Moroccans residing in Belgium using 15 STRs of the Identifiler kit". J Forensic Sci. 51:442-444. (2006) Online citation.


Sample Information:

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Sample Name: Morocco

Sample UID: SA001841O

Sample Description:This sample consists of healthy, unrelated Arab and Berber individuals from Morocco.

Number of Chromosomes: 80

Relation to Other Samples:

References:
- Terreros MC, Martinez L, Herrera RJ. "Polymorphic Alu insertions and genetic diversity among African populations". Hum Biol. 77:675-704. (2005) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccons

Sample UID: SA003391Q

Sample Description:This sample consists of Moroccan individuals from Madrid. This sample is part of the training sets that were used to asses the 34-plex Ancestry informative marker set assay.

Number of Chromosomes: 96

Relation to Other Samples:

References:
- Phillips C, Prieto L, Fondevila M, Salas A, Gómez-Tato A, Alvarez-Dios J, Alonso A, Blanco-Verea A, Brión M, Montesino M, Carracedo A, Lareu MV. "Ancestry analysis in the 11-M Madrid bomb attack investigation". PLoS One. 4:e6583. (2009) Online citation.


Sample Information:

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Sample Name: Moroccan

Sample UID: SA003096S

Sample Description:This sample consists of Moroccan individuals undergoing coronary angiography. This sample includes the individuals whose angiograms were normal and are the conrol group for the study. The study was approved by the Review Board of the National League of Cardiology, Rabat, Morocco.

Number of Chromosomes: 380

Relation to Other Samples:

References:
- Bennouar N, Allami A, Azeddoug H, Bendris A, Laraqui A, El Jaffali A, El Kadiri N, Benzidia R, Benomar A, Fellat S, Benomar M. "Thermolabile Methylenetetrahydrofolate Reductase C677T Polymorphism and Homocysteine Are Risk Factors for Coronary Artery Disease in Moroccan Population". J Biomed Biotechnol. 1:80687. (2007) Online citation.


Sample Information:

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Sample Name: Moroccan

Sample UID: SA002176Q

Sample Description:This sample consists of authentic native moroccans from representative geographic areas of Morocco : 34 from the north (region of Tanger and Tetouan), 76 from the center (region of Rabat and casblanca) and 57 from the south (region of Marrakech and Agadir).

Number of Chromosomes: 334

Relation to Other Samples:

References:
- Letter to the Editor "Frequency of the CCR5Delta 32 Allele in the Moroccan Population". AIDS Research and Human Retroviruses. 16:87-89.. (2000)


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccans

Sample UID: SA003273P

Sample Description:This sample consists of Moroccans (arabs from central-souther region: Abda, Chaoui, Doukkala and Tadla.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 200

Relation to Other Samples:

References:
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.

- Valveny N, Esteban E, Kandil M, Moral P. "APO E polymorphism in Spanish and Moroccan populations". Clin Genet. 51:354-6. (1997) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccans

Sample UID: SA003314L

Sample Description:This sample consists of Moroccans from Rabat area.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 336

Relation to Other Samples:

References:
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.

- Lahlali-Kacemi N, Bamou Y, Guedira A, Hassani M, Visvikis S, Siest G, Alami N, Kabbaj O, Lahrichi M. "Apolipoprotein E polymorphism in a Moroccan population: allele frequency and relation to plasma lipid concentrations". Ann Biol Clin (Paris). 60:73-8. (2002) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: South Moroccans

Sample UID: SA003437R

Sample Description:This sample consists of unrelated individuals who speak Berber from Marrakesh, Beni Mellal,Errachidia and Smara, Southern Morocco.

Number of Chromosomes: 168

Relation to Other Samples:

References:
- Garagnani P, Laayouni H, González-Neira A, Sikora M, Luiselli D, Bertranpetit J, Calafell F. "Isolated populations as treasure troves in genetic epidemiology: the case of the Basques". Eur J Hum Genet. 17:1490-4. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Moroccans

Sample UID: SA004055O

Sample Description:This sample consists of individuals of self-declared Moroccan ancestry, resident in Madrid, Spain.

Number of Chromosomes: 82

Relation to Other Samples:

References:
- Bulbul O, Filoglu G, Altuncul H, Aradas AF, Ruiz Y, Fondevila M, Phillips C, Carracedo A, Kriegel AK, Schneider PM "A SNP multiplex for the simulataneous prediction of biogeographic ancestry and pigmentaion type". Forensic science International:Genetics Supplement Series 3 e500-501. (2011)


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Casablanca

Sample UID: SA004232L

Sample Description:This sample consists of Moroccons from Casablanca, Morocco.

Number of Chromosomes: 60

Relation to Other Samples:

References:
- Engelken J1, Carnero-Montoro E2, Pybus M2, Andrews GK3, Lalueza-Fox C2, Comas D2, Sekler I4, de la Rasilla M5, Rosas A6, Stoneking M7, Valverde MA8, Vicente R8, Bosch E2 "Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa". PLoS Genet 10:(2014) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Rabat

Sample UID: SA004233M

Sample Description:This sample consists of individuals from Rabat, Morocco.

Number of Chromosomes: 60

Relation to Other Samples:

References:
- Engelken J1, Carnero-Montoro E2, Pybus M2, Andrews GK3, Lalueza-Fox C2, Comas D2, Sekler I4, de la Rasilla M5, Rosas A6, Stoneking M7, Valverde MA8, Vicente R8, Bosch E2 "Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa". PLoS Genet 10:(2014) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nador

Sample UID: SA004234N

Sample Description:This sample consists of individuals from Nador, Morocco.

Number of Chromosomes: 60

Relation to Other Samples:

References:
- Engelken J1, Carnero-Montoro E2, Pybus M2, Andrews GK3, Lalueza-Fox C2, Comas D2, Sekler I4, de la Rasilla M5, Rosas A6, Stoneking M7, Valverde MA8, Vicente R8, Bosch E2 "Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa". PLoS Genet 10:(2014) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

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© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan