ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
FrenchPO000111DFrenchIndo-European

Synonyms:
Geographic Location1:  51N, 3E; 42.5N, 7.5E  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources:  Fondation Jean Dausset - CEPH Record    Ethnologue: Language Map Record    Ethnologue: Language Description Record    Ethnologue: Country Description Record    
References: See references
Population Description: France is a country that has undergone thousands of years of migrations and invasions. The nation itself underwent considerable expansions up until the middle of the 17th century. It is for these reasons that the ethnic French person is really a mixture of many different groups, namely Germanic, Celtic, and Roman populations. It is also this reason that even by the end of the 18th century, the majority of the country did not speak French. To overcome this obstacle, the French nation created a rather successful law that defined a person by their geographical boundaries. It was the "law of the soil" which claimed that the ethic identity of an individual and their residence were inseparable. Therefore, everyone who was within France's borders became assimilated into the mainstream French culture and identity. This also connects with France's long history of immigration. There are many immigrants in the country. However, generally they are absorbed into the French culture rather than distinguishing themselves as a distinct group. There are several ethic minorities in France such as the Flemish, Basque, and Alsacians who hold onto their identity as distinct from the rest of the culture. The modern French language is actually a dialect of a language from northern section of the country. The modern French language developed in the Parisian Basin during medieval times. The vast majority of the population of the country now speaks this Romance language. The prevailing religion of the French population is Roman Catholicism. There is also a small yet significant Ashkenazi Jewish population in France.
References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000651M

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 94

Relation to Other Samples: Superset of sample SA000510G

References:
- Batzer MA, Arcot SS, Phinney JW, Alegria-Hartman M, Kass DH, Milligan SM, Kimpton C, Gill P, Hochmeister M, Ioannou PA, Herrera RJ, Boudreau DA, Scheer WD, Keats BJB, Deininger PL, Stoneking M. "Genetic variation of recent Alu Insertions in human populations". J Mol Evol 42:22-29. (1996) Online citation.

- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000666S

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 144

Relation to Other Samples: Superset of sample SA000510G

References:
- Arcot SS, Adamson AW, Risch GW, LaFleur J, Robichaux MB, Lamerdin JE, Carrano AV, Batzer MA "High-resolution cartography of recently integrated human chromosome 19-specific Alu fossils". J Mol Biol 281:843-56. (1998) Online citation.

- Batzer MA, Arcot SS, Phinney JW, Alegria-Hartman M, Kass DH, Milligan SM, Kimpton C, Gill P, Hochmeister M, Ioannou PA, Herrera RJ, Boudreau DA, Scheer WD, Keats BJB, Deininger PL, Stoneking M. "Genetic variation of recent Alu Insertions in human populations". J Mol Evol 42:22-29. (1996) Online citation.

- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000686U

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 144

Relation to Other Samples: Superset of sample SA000544N

References:
- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.

- Romualdi C, Balding D, Nasidze IS, Risch G, Robichaux M, Sherry ST, Stoneking M, Batzer MA, Barbujani G. "Patterns of human diversity, within and among continents, inferred from Biallilic DNA polymorphisms". Genome Res 12:602-612. (2002) Online citation.

- Stoneking M, Fontius JJ, Clifford SL, Soodyall H, Arcot SS, Saha N, Jenkins T, Tahir MA, Deininger PL, Batzer MA. "Alu insertion polymorphisms and human evolution: evidence for a larger population size in Africa ". Genome Res 7:1061-71. (1997) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French, unrelated CEPH

Sample UID: SA000123G

Sample Description:French sample of unrelated members of the CEPH kindreds.

Number of Chromosomes: 40

Relation to Other Samples:

References:
- Jorde LB, Bamshad MJ, Watkins WS, Zenger R, Fraley AE, Krakowiak PA, Carpenter KD, Soodyall H, Jenkins T, Rogers AR. "Origins and affinities of modern humans: a comparison of mitochondrial and nuclear genetic data.". Am. J. Hum. Genet. 57:523-538. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000510G

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 88

Relation to Other Samples:

References:
- Batzer MA, Arcot SS, Phinney JW, Alegria-Hartman M, Kass DH, Milligan SM, Kimpton C, Gill P, Hochmeister M, Ioannou PA, Herrera RJ, Boudreau DA, Scheer WD, Keats BJB, Deininger PL, Stoneking M. "Genetic variation of recent Alu Insertions in human populations". J Mol Evol 42:22-29. (1996) Online citation.

- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000544N

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 106

Relation to Other Samples: Superset of sample SA000510G

References:
- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000554O

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 144

Relation to Other Samples: Superset of sample SA000510G

References:
- Batzer MA, Arcot SS, Phinney JW, Alegria-Hartman M, Kass DH, Milligan SM, Kimpton C, Gill P, Hochmeister M, Ioannou PA, Herrera RJ, Boudreau DA, Scheer WD, Keats BJB, Deininger PL, Stoneking M. "Genetic variation of recent Alu Insertions in human populations". J Mol Evol 42:22-29. (1996) Online citation.

- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000594S

Sample Description:This sample consists of French Caucasions. The sample was collected from different regions of France including Strasbourg, Grenoble, Marseille, Lille, Nantes, and Paris.

Number of Chromosomes: 144

Relation to Other Samples: Superset of SA000544N

References:
- Monson KL, Moisan J-P, Pascal O, McSween M, Aubert D, Guisti A, Budowle B, Lavergne L. "Description and analysis of allele distribution for four VNTR markers in French and French Canadian populations". Hum Hered 45:135-143. (1995) Online citation.

- Stoneking M, Fontius JJ, Clifford SL, Soodyall H, Arcot SS, Saha N, Jenkins T, Tahir MA, Deininger PL, Batzer MA. "Alu insertion polymorphisms and human evolution: evidence for a larger population size in Africa ". Genome Res 7:1061-71. (1997) Online citation.

- Zoossmann-Disken A, Ticher A, Hakim I, Goldwitch Z, Rubinstein A, Bonne-Tamir B. "Genetic affinities of Ethiopian Jews. affinities of Ethiopian Jews". Israel J. of Med. Sciences 27:245. (1991) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA001064L

Sample Description:This sample consists of healthly French (22% female) anonymous blood donors. These subjects were controls in a study of mental disease and none had a first degree relative affected with "probable schizophrenia". Written informed consent was obtained from all participants.

Number of Chromosomes: 100

Relation to Other Samples:

References:
- Dubertret C, Gorwood P, Gouya L, Deybach JC, Ades J. "Association and excess of transmission of a DRD2 haplotype in a sample of French schizophrenic patients". Schizophr Res. 49:203-212. (2001) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA000848U

Sample Description:This sample consists of unrelated individuals selected from adults residing in eastern France.

Number of Chromosomes: 1716

Relation to Other Samples:

References:
- Ng MC, Wang Y, So WY, Cheng S, Visvikis S, Zee RY, Fernandez-Cruz A, Lindpaintner K, Chan JC. "Ethnic differences in the linkage disequilibrium and distribution of single-nucleotide polymorphisms in 35 candidate genes for cardiovascular diseases". Genomics 83: 559-65. (2004) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French, HGDP-CEPH

Sample UID: SA001503J

Sample Description:This sample form various regions of France is part of the Human Genome Diversity Cell Line Panel collected by the Human Genome Diversity Project (HGDP) and the Foundation Jean Dausset (CEPH). This sample consists of unrelated individuals and was collected with proper informed consent.

Note: In many publications subset H952 of the HGDP panel (with first and second degree relatives excluded from the original set) was typed and for this population that decreases the sample size from 29 to 28 individuals.

Number of Chromosomes: 58

Relation to Other Samples:

References:
- Rosenberg NA, Pritchard JK, Weber JL, Cann HM, Kidd KK, Zhivotovsky LA, Feldman MW. "Genetic structure of human populations". Science 298:2381-2385. (2002) Online citation.

- Rosenberg NA. "Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives.". Ann Hum Genet. 70:841-847. (2006) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French (Brittany)

Sample UID: SA001863S

Sample Description:This sample consists of unrelated individuals from Brest, France.

Number of Chromosomes: 200

Relation to Other Samples:

References:
- Libert F, Cochaux P, Beckman G, Samson M, Aksenova M, Cao A, Czeizel A, Claustres M, de la Rua C, Ferrari M, Ferrec C, Glover G, Grinde B, Guran S, Kucinskas V, Lavinha J, Mercier B, Ogur G, Peltonen L, Rosatelli C, Schwartz M, Spitsyn V, Timar L, Beckman L, Parmentier M, Vassart G "The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe". Hum Mol Genet. 7:399-406.. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French (Montpellier)

Sample UID: SA001864T

Sample Description:This sample consists of unrelated individuals from Montpellier, France.

Number of Chromosomes: 198

Relation to Other Samples:

References:
- Libert F, Cochaux P, Beckman G, Samson M, Aksenova M, Cao A, Czeizel A, Claustres M, de la Rua C, Ferrari M, Ferrec C, Glover G, Grinde B, Guran S, Kucinskas V, Lavinha J, Mercier B, Ogur G, Peltonen L, Rosatelli C, Schwartz M, Spitsyn V, Timar L, Beckman L, Parmentier M, Vassart G "The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe". Hum Mol Genet. 7:399-406.. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French-CEPH

Sample UID: SA001636Q

Sample Description:This sample consists of individuals from the CEPH French families.

Number of Chromosomes: 24

Relation to Other Samples:

References:
- Yoshiura KI et al. "A SNP in the ABCC11 gene is the determinant of human earwax type.". Nat Genet. 38:324-330. (2006) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Lille

Sample UID: SA003639V

Sample Description:This sample consists of participants recruited as part of the World health organization -MONICA population survey conducted from 1995 to 1997 in Lille urban community in Northern France.

Number of Chromosomes: 2390

Relation to Other Samples:

References:
- Legry V, Cottel D, Ferrières J, Arveiler D, Andrieux N, Bingham A, Wagner A, Ruidavets JB, Ducimetière P, Amouyel P, Meirhaeghe A. "Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study". Metabolism. 58:971-5. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Bas-Rhin

Sample UID: SA003640N

Sample Description:This sample consists of participants recruited as part of the World health organization -MONICA population survey conducted from 1995 to 1997 in Bas-Rhin urban community in Eastern France.

Number of Chromosomes: 2262

Relation to Other Samples:

References:
- Legry V, Cottel D, Ferrières J, Arveiler D, Andrieux N, Bingham A, Wagner A, Ruidavets JB, Ducimetière P, Amouyel P, Meirhaeghe A. "Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study". Metabolism. 58:971-5. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Haute-Garonne

Sample UID: SA003641O

Sample Description:This sample consists of participants recruited as part of the World health organization -MONICA population survey conducted from 1995 to 1997 in Haute-Garonne county in Southern France.

Number of Chromosomes: 2364

Relation to Other Samples:

References:
- Legry V, Cottel D, Ferrières J, Arveiler D, Andrieux N, Bingham A, Wagner A, Ruidavets JB, Ducimetière P, Amouyel P, Meirhaeghe A. "Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study". Metabolism. 58:971-5. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Paris

Sample UID: SA002734Q

Sample Description:This sample consists of participants from Paris, France who were part of multicenter case-conrol study conducted from 2002-2005 in 12 centres from 8 European countries. This study is called ARCAGE (Alcohol-related Cancers and genetic susceptibility in Europe). All participants were interviewed with a structured questionnaire.

Number of Chromosomes: 256

Relation to Other Samples:

References:
- Hashibe M, McKay JD, Curado MP, Oliveira JC, Koifman S, Koifman R, Zaridze D, Shangina O, Wünsch-Filho V, Eluf-Neto J, Levi JE, Matos E, Lagiou P, Lagiou A, Benhamou S et.al. "Multiple ADH genes are associated with upper aerodigestive cancers". Nat Genet. 40:707-9. (2008) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Lille

Sample UID: SA002454P

Sample Description:This sample consists of unrelated individuals from Lille, France.

Number of Chromosomes: 202

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Reims

Sample UID: SA002455Q

Sample Description:This sample consists of unrelated individuals from Reims, France.

Number of Chromosomes: 552

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: East France

Sample UID: SA002456R

Sample Description:This sample consists of unrelated individuals from Eastern France.

Number of Chromosomes: 582

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Paris

Sample UID: SA002457S

Sample Description:This sample consists of unrelated individuals from Paris, France.

Number of Chromosomes: 588

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: France

Sample UID: SA003109N

Sample Description:This sample consists of subjects from Southern France.

Number of Chromosomes: 110

Relation to Other Samples:

References:
- Falchi A, Barsotelli M, Giovannoni L, Varesi L, Vona G "Prevalance of MTHFR gene polymorphisms among Meditarenean populations: a possible genetic selection from Malaria?". 554-556. (2006)


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: South France

Sample UID: SA002459U

Sample Description:This sample consists of individuals from South France.

Number of Chromosomes: 652

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nice

Sample UID: SA002462O

Sample Description:This sample consists of unrelated individuals from Nice, France.

Number of Chromosomes: 248

Relation to Other Samples:

References:
- Lucotte G, Mercier G. "Distribution of the CCR5 gene 32-bp deletion in Europe". J Acquir Immune Defic Syndr Hum Retrovirol. 19:174-7. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: France

Sample UID: SA002405L

Sample Description:This sample consists of individuals from Paris, France.

Number of Chromosomes: 184

Relation to Other Samples:

References:
- Magierowska M, Lepage V, Boubnova L, Carcassi C, de Juan D, Djoulah S, El Chenawi F, Grunnet N, Hallé L, Ivanova R, Jungerman M, Naumova E, Petrany G, Sonnerborg A, Stavropoulos C, Thorsby E, Vu-Trieu A, Debré P, Theodorou I, Charron D "Distribution of the CCR5 gene 32 base pair deletion and SDF1-3'A variant in healthy individuals from different populations". Immunogenetics. 48:417-9. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French (CEPH)

Sample UID: SA002057O

Sample Description:This sample consists of French individuals. This sample is part of the Human Genome Diversity Cell Line Panel collected by the Human Genome Diversity Project (HGDP) and the Foundation Jean Dausset (CEPH).

Number of Chromosomes: 48

Relation to Other Samples:

References:
- Ingram CJ, Elamin MF, Mulcare CA, Weale ME, Tarekegn A, Raga TO, Bekele E, Elamin FM, Thomas MG, Bradman N, Swallow DM. "A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?". Hum Genet. 120:779-788. (2007) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA002861R

Sample Description:This sample consists of unrelated French individuals, mainly living in Rheims, France. The donors were selected at random, irrespective of skin color, and their phenotypic data were unavailable.

Number of Chromosomes: 196

Relation to Other Samples:

References:
- Yuasa I, Umetsu K, Harihara S, Kido A, Miyoshi A, Saitou N, Dashnyam B, Jin F, Lucotte G, Chattopadhyay PK, Henke L, Henke J. "Distribution of two Asian-related coding SNPs in the MC1R and OCA2 genes". Biochem Genet. 45:535-42. (2007) Online citation.

- Yuasa I, Umetsu K, Harihara S, Miyoshi A, Saitou N, Park KS, Dashnyam B, Jin F, Lucotte G, Chattopadhyay PK, Henke L, Henke J "OCA2 481Thr, a hypofunctional allele in pigmentation, is characteristic of northeastern Asian populations". J Hum Genet 52:690-3.. (2007) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA002650N

Sample Description:This sample consists of unrelated French Caucasians recruited from hoapital wards and outpatient clinics throughout the Champagne-Ardennes region in France.

Number of Chromosomes: 106

Relation to Other Samples:

References:
- Mercier G, Turpin JC, Lucotte G "Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson's disease: no association found". J Neurol. 246:45-7. (1999) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA002941Q

Sample Description:This sample consists of French individuals who were part of a case-control study. The study was conducted in France between 1997 and 2001 in three general hospitals located in Paris. This sample includes the non-urological control treated at the medical departments for non-tobacco related diseases. Detailed information on sociodemographic characteristics, medical history and occupational history was collected. All participants signed informed consent agreements and the study was approved by the Ethical Committee for the Protection of human subjects at Kremblin-Bicetre Hospital (France).

Number of Chromosomes: 332

Relation to Other Samples:

References:
- Michiels S, Laplanche A, Boulet T, Dessen P, Guillonneau B, Méjean A, Desgrandchamps F, Lathrop M, Sarasin A, Benhamou S "Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk". Carcinogenesis. 30:763-8. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Bordeaux

Sample UID: SA002080K

Sample Description:This sample consists of men and women from Bordeaux, France.

Number of Chromosomes: 320

Relation to Other Samples:

References:
- Borras E, Coutelle C, Rosell A, Fernandez-Muixi F, Broch M, Crosas B, Hjelmqvist L, Lorenzo A, Gutierrez C, Santos M, Szczepanek M, Heilig M, Quattrocchi P, Farres J, Vidal F, Richart C, Mach T, Bogdal J, Jornvall H, Seitz HK, Couzigou P, Pares X "Genetic polymorphism of alcohol dehydrogenase in europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1". Hepatology. 31:984-9. (2000) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA003117M

Sample Description:This sample consists of healthy volunteers from France who were recruited either in the northeast(Lorraine) or east (Burgundy and Franche Comte).

Number of Chromosomes: 712

Relation to Other Samples:

References:
- Guéant-Rodriguez RM, Guéant JL, Debard R, Thirion S, Hong LX, Bronowicki JP, Namour F, Chabi NW, Sanni A, Anello G, Bosco P, Romano C, Amouzou E, Arrieta HR, Sánchez BE, Romano A, Herbeth B, Guilland JC, Mutchinick OM "Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations". Am J Clin Nutr. 83:701-7. (2006) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA002483R

Sample Description:This sample consists of French individuals.

Number of Chromosomes: 460

Relation to Other Samples:

References:
- Stephens JC, Reich DE, Goldstein DB, Shin HD, Smith MW et.al. "Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes". Am J Hum Genet. 62:1507-15. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Brest

Sample UID: SA002568V

Sample Description:This sample consists of French individuals from Brest,France.

Number of Chromosomes: 214

Relation to Other Samples:

References:
- Lucotte G, Mercier G "Frequency of the coreceptor CCR5 gene delta 32 mutation in different French regions". C R Acad Sci III. 321:409-13. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Biarritz

Sample UID: SA002571P

Sample Description:This sample consists of French individuals from Biarritz, France.

Number of Chromosomes: 222

Relation to Other Samples:

References:
- Lucotte G, Mercier G "Frequency of the coreceptor CCR5 gene delta 32 mutation in different French regions". C R Acad Sci III. 321:409-13. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Perpignan

Sample UID: SA002572Q

Sample Description:This sample consists of French individuals from Perpignan, France.

Number of Chromosomes: 204

Relation to Other Samples:

References:
- Lucotte G, Mercier G "Frequency of the coreceptor CCR5 gene delta 32 mutation in different French regions". C R Acad Sci III. 321:409-13. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Ajaccio

Sample UID: SA002573R

Sample Description:This sample consists of French individuals from Ajaccio, France.

Number of Chromosomes: 208

Relation to Other Samples:

References:
- Lucotte G, Mercier G "Frequency of the coreceptor CCR5 gene delta 32 mutation in different French regions". C R Acad Sci III. 321:409-13. (1998) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Lille

Sample UID: SA003315M

Sample Description:This sample consists of French individuals.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 278

Relation to Other Samples:

References:
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.

- Luc G, Bard JM, Arveiler D, Evans A, Cambou JP, Bingham A, Amouyel P, Schaffer P, Ruidavets JB, Cambien F, et al. "Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction. The ECTIM Study". Arterioscler Thromb 14:1412-9.. (1994) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Strasbourg

Sample UID: SA003316N

Sample Description:This sample consists of French individuals.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 318

Relation to Other Samples:

References:
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.

- Luc G, Bard JM, Arveiler D, Evans A, Cambou JP, Bingham A, Amouyel P, Schaffer P, Ruidavets JB, Cambien F, et al. "Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction. The ECTIM Study". Arterioscler Thromb 14:1412-9.. (1994) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Toulouse

Sample UID: SA003317O

Sample Description:This sample consists of French individuals.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 342

Relation to Other Samples:

References:
- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.

- Luc G, Bard JM, Arveiler D, Evans A, Cambou JP, Bingham A, Amouyel P, Schaffer P, Ruidavets JB, Cambien F, et al. "Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction. The ECTIM Study". Arterioscler Thromb 14:1412-9.. (1994) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: France,Strasbourg

Sample UID: SA002699A

Sample Description:Specimens were taken from consecutive newborns from newborn screening centres in Department du Bas-rhin. Specimens consisted of the remainder of blood spots used by the newborn screening program. This study was conducted under the auspices of the International Clearinghouse for Birth Defect Monitoring Systems (ICBDMS) and was coordinated through its head office, the International Center on Birth Defects. Local review boards approved the study.In all cases personal identifiers were removed before data were provided to ICBD for epidemiological analysis.

Number of Chromosomes: 356

Relation to Other Samples:

References:
- Wilcken B, Bamforth F, Li Z, Zhu H, Ritvanen A, Renlund M, Stoll C, Alembik Y, Dott B, Czeizel AE, Gelman-Kohan Z, Scarano G, Bianca S, Ettore G, Tenconi R, Bellato S, Scala I, Mutchinick OM, López MA, de Walle H, Hofstra R, Joutchenko L, Kavteladze L, Bermejo E, Martínez-Frías ML, Gallagher M, Erickson JD, Vollset SE, Mastroiacovo P, Andria G, Botto LD. "Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): findings from over 7000 newborns from 16 areas world wide". J Med Genet. 40:619-25.. (2003) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Paris

Sample UID: SA003331K

Sample Description:This sample consists of French individuals.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 986

Relation to Other Samples:

References:
- Bailleul S, Couderc R, Landais V, Lefèvre G, Raichvarg D, Etienne J. "Direct phenotyping of human apolipoprotein E in plasma: application to population frequency distribution in Paris (France)". Hum Hered. 43:159-65.. (1993) Online citation.

- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nancy

Sample UID: SA003339S

Sample Description:This sample consists of French individuals.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 1508

Relation to Other Samples:

References:
- Bohnet K, Regis-Bailly A, Vincent-Viry M, Schlenck A, Gueguen R, Siest G, Visvikis S. "Apolipoprotein E genotype epsilon 4/epsilon 2 in the STANISLAS Cohort Study--dominance of the epsilon 2 allele?". Ann Hum Genet. 60:509-16.. (1996) Online citation.

- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: French

Sample UID: SA003995A

Sample Description:This sample consists of control group of healthy blood bank donors from the Paris area.

Number of Chromosomes: 322

Relation to Other Samples:

References:
- Laplanche JL, Laupretre, Brandel JP et al. "Molecular genetics of prion diseases in France". Neurology 44:2347. (1994)


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: France

Sample UID: SA004041J

Sample Description:This sample consists of individuals from Paris-Creteil, France . This sample is part of the EUREYE(European Eye Study). The EUREYE Study is multicenter, population-based cross-sectional study from 7 study centers, Bergen, Norway; Tallinn, Estonia; Belfast, Northern Ireland, United Kingdom; Paris-Creteil, France; Verona, Italy; Thessaloniki, Greece; and Alicante, Spain. were chosen primarily to maximize the range of latitude and lifestyle behaviors, including diet.

Number of Chromosomes: 1232

Relation to Other Samples:

References:
- Walsh S, Wollstein A, Liu F, Chakravarthy U, Rahu M, Seland JH, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Vioque J, Fletcher AE, Ballantyne KN, Kayser "DNA-based eye colour prediction across Europe with the IrisPlex system". Forensic Sci Int Genet. (Epub, ahead of print) (2011) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: France (Paris)

Sample UID: SA004545S

Sample Description:This sample consists of french individuals from Paris, France. This sample was typed as part of the collaborative exercise by the participating laboratory as part of the International Society for Forensic Genetics (GHEP-ISFG) working commission on autosomal indels for human identification. This study was approved by vote at the GHEP-ISFG general meeting and complies with the ethical principles of the 2000 Helsinki Declaration of the World Medical Association. The samples used in this collaborative exercise were anonymised DNA extracts previously obtained from healthy unrelated individuals who consented to participate in this study under strictly confidential conditions.

Number of Chromosomes: 200

Relation to Other Samples:

References:
- Pereira R, Alves C, Aler M, Amorim A, ArAvalo C, Betancor E, Braganholi D, Bravo ML, Brito P, Builes JJ, Burgos G, Carvalho EF, Castillo A, Catanesi CI, Cicarelli RMB, Coufalova P, Dario P, D'Amato ME, Davison S, Ferragut J, Fondevila M, Furfuro S, Garcia O, Gaviria A, Gomes I, Gonzalez E, Gonzalez-Linan A, Gross TE, Hernanndez A, Huang Q, Jimenez S, Jobim LF, Lopez-Parra AM, Marino M, Marques S, Marti­nez-Cortes G, Masciovecchio V, Parra D, Penacino G, Pinheiro MF, Porto M, Posada Y, Restrepo C, Ribeiro T, Rubio L, Sala A, Santurtun A, Soli­s LS, Souto L, Streitemberger E, Torres A, Vilela-Lamego C, Yunis JJ, Yurrebaso I, Gusmao L. "A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations". Forensic Sci Int Genet. 32:18-25. (2017) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

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© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan