ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
NahuasPO000508N

Synonyms:
Geographic Location1:  20N, 101.5W; 16.5N, 99W  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: 
References: See references
Population Description: Being curated
References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas-Guerrero

Sample UID: SA001110D

Sample Description:This sameple consists of unrelated individuals belonging to the Nahuas-Guerrero, a Mexican indigenous population.

Number of Chromosomes: 80

Relation to Other Samples:

References:
- Buentello-Malo L, Penaloza-Espinosa RI, Loeza F, Salamanca-Gomez F, Cerda-Flores RM. "Genetic structure of seven Mexican indigenous populations based on five polymarker loci". Am J Hum Biol 15:23-28. (2003) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas-Xochimilco

Sample UID: SA001111E

Sample Description:This sameple consists of unrelated individuals belonging to the Nahuas-Xochimilco, a Mexican indigenous population.

Number of Chromosomes: 92

Relation to Other Samples:

References:
- Buentello-Malo L, Penaloza-Espinosa RI, Loeza F, Salamanca-Gomez F, Cerda-Flores RM. "Genetic structure of seven Mexican indigenous populations based on five polymarker loci". Am J Hum Biol 15:23-28. (2003) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahua

Sample UID: SA001675T

Sample Description:This sample consists of Nahua living in teh city of Tlapa, Guerrero, Mexico. These individuals were selected as a subset of individuals showing low European ancestry.

Number of Chromosomes: 40

Relation to Other Samples:

References:
- Shriver MD, Mei R, Parra EJ, Sonpar V, Halder I, Tishkoff SA, Schurr TG, Zhadanov SI, Osipova LP, Brutsaert TD, Friedlaender J, Jorde LB, Watkins WS, Bamshad MJ, Gutierrez G, Loi H, Matsuzaki H, Kittles RA, Argyropoulos G, Fernandez JR, Akey JM, Jones KW. "Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation". Hum Genomics. 2:81-89. (2005) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahua

Sample UID: SA003472Q

Sample Description:This sample consists of Nahuas from Central Mexico. This sample was provided by Marta E Alarcon-Riquelme. The subjects studied were all healthy and not first-degree relatives of each other based on self-reporting.

Number of Chromosomes: 58

Relation to Other Samples:

References:
- Kosoy R, Nassir R, Tian C, White PA, Butler LM, Silva G, Kittles R, Alarcon-Riquelme ME, Gregersen PK, Belmont JW, De La Vega FM, Seldin MF. "Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America". Hum Mutat 30:69-78. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas

Sample UID: SA003540M

Sample Description:This sample consists of Nahuas. Written informed consent was obtained from each participant. The study was approved by the Human Ethics Committees of the participating institutes.

Number of Chromosomes: 176

Relation to Other Samples:

References:
- Fujihara J, Ueki M, Yasuda T, Iida R, Soejima M, Koda Y, Kimura-Kataoka K, Kato H, Panduro A, Tongu M, Takeshita H. "Functional and Genetic Survey of All Known Single-Nucleotide Polymorphisms Within the Human Deoxyribonuclease I Gene in Wide-Ranging Ethnic Groups". DNA Cell Biol. (Epub, ahead of print) (2011) Online citation.

- Yasuda T, Ueki M, Takeshita H, Fujihara J, Kimura-Kataoka K, Iida R, Tsubota E, Soejima M, Koda Y, Kato H, Panduro A. "A biochemical and genetic study on all non-synonymous single nucleotide polymorphisms of the gene encoding human deoxyribonuclease I potentially relevant to autoimmunity". Int J Biochem Cell Biol. 42:1216-25. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas

Sample UID: SA003674U

Sample Description:This sample consists of Nahuas from Mexico. All the Mexican natives and their ancestors (two generations) were born in the same community and spoke their own native language.

Number of Chromosomes: 534

Relation to Other Samples:

References:
- Acuña-Alonzo V et al. "A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans". Hum Mol Genet 19:2877-85. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas

Sample UID: SA003254O

Sample Description:This sample consists of Nahuas from (Ixhuatlancillo and Necoxtla.

Note: This sample information is not fully curated. For additional information about the sample, consult the publications under "References". The sample was entered as part of data submission by Eisenberg DA.

Number of Chromosomes: 240

Relation to Other Samples:

References:
- Cruz-Fuentes CS, González-Sobrino BZ, Gómez-Sanchez A, Martínez Rueda H, Chávez-Eakle RA, Serrano Sánchez C. "Distribution of apolipoprotein E alleles in coras and huicholes from Nayarit and Nahuas and Mestizos from Veracruz, Mexico". Hum Biol. 77:867-72. (2005) Online citation.

- Eisenberg DA, Kuzawa, CW, Hayes MG "Worldwide allele frequencies of the human apolipoprotein E (APOE) gene: climate, local adaptations and evolutionary history". American Journal of Physical Anthropology 143:100-11. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nahuas

Sample UID: SA004188V

Sample Description:This sample consists of randomly collected unrelated healthy subjects of Nahuas.

Number of Chromosomes: 138

Relation to Other Samples:

References:
- Fujihara J, Yasuda T, Kato H, Yuasa I, Panduro A, Kunito T, Takeshita H. "Genetic variants associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase show wide variation across multiple populations". Arch Toxicol. 85:119-25. (2011) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

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© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan