ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
HazaraPO000575R

Synonyms:
Geographic Location1:  38N, 56E; 24N, 73E  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: 
References: See references
Population Description: Being curated
References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Hazara

Sample UID: SA001909T

Sample Description:This sample consists of unrelated Hazara who speak an Indo-European language.

Number of Chromosomes: 62

Relation to Other Samples:

References:
- Khaliq S, Hameed A, Ayub Q, Mazhar K, Mohyuddin A, Mansoor A, Mehdi SQ "Frequency of CCR5 Gene 32-bp deletion in Pakistani ethnic groups". Genet Test. 6:123-7. (2002) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Hazara, HGDP-CEPH

Sample UID: SA001477T

Sample Description:This sample from Pakistan is part of the Human Genome Diversity Cell Line Panel collected by the Human Genome Diversity Project (HGDP) and the Foundation Jean Dausset (CEPH). This sample consists of unrelated individuals and was collected with proper informed consent.

Note: The number of individuals in the H1048 are 24 with one individual excluded from set H1064. In many publications subset H952 of the HGDP panel (with first and second degree relatives excluded from the original set) was typed and for this population that decreases the sample size from 24 to 22 individuals and for subset H971 of the HGDP panel(with first degree relatives excluded) the sample size decreases from 24 to 23 individuals.

Number of Chromosomes: 50

Relation to Other Samples:

References:
- Rosenberg NA, Pritchard JK, Weber JL, Cann HM, Kidd KK, Zhivotovsky LA, Feldman MW. "Genetic structure of human populations". Science 298:2381-2385. (2002) Online citation.

- Rosenberg NA. "Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives.". Ann Hum Genet. 70:841-847. (2006) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Hazara, HGDP-CEPH

Sample UID: SA002258R

Sample Description:This sample from Pakistan is part of the Human Genome Diversity Cell Line Panel collected by the Human Genome Diversity Project (HGDP) and the Foundation Jean Dausset (CEPH). This sample consists of unrelated individuals and was collected with proper informed consent.

This sample is known as dataset "H1048" and is a subset of SA001477T.

Number of Chromosomes: 44

Relation to Other Samples: Subset of SA001477T

References:
- Conrad DF, Jakobsson M, Coop G, Wen X, Wall JD, Rosenberg NA, Pritchard JK. "A worldwide survey of haplotype variation and linkage disequilibrium in the human genome". Nat Genet. 38:1251-1260. (2006) Online citation.

- Rosenberg NA. "Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives.". Ann Hum Genet. 70:841-847. (2006) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Hazara

Sample UID: SA003075P

Sample Description:This sample consists of healthy, adult individuals from Hazara tribe, a tribal group from northern Pakistan. Informed consent were obtained from all the individuals.

Number of Chromosomes: 64

Relation to Other Samples:

References:
- Mansoor A, Mazhar K, Ali L, Muazzam AG, Siddiqi S, Usman S. "Prevalence of the C677T single-nucleotide polymorphism in the methylenetetrahydrofolate reductase gene among Pakistani ethnic groups". Genet Test Mol Biomarkers. 13:521-6. (2009) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Hazaras

Sample UID: SA002140H

Sample Description:This sample consists of unrelated individuals collected by Dr. Qasim Mehdi and colleagues in Pakistan.

Number of Chromosomes: 60

Relation to Other Samples:

References:
- Li H, Mukherjee N, Soundararajan U, Tarnok Z, Barta C, Khaliq S, Mohyuddin A, Kajuna SLB, Mehdi SQ, Kidd JR, Kidd KK. "Geographically Separate Increases in the Frequency of the Derived ADH1B*47His Allele in East and West Asia". Am J Hum Genet 81:842-6. (2007) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

Top


© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan