ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Population Information

NameALFRED UIDPrimary LanguageLanguage Family
KeralitePO000672PMalayalamDravidian

Synonyms: Malayalee ;
Geographic Location1:  13N, 75E; 8N, 77.5E  

Sites typed for this population: View List
Population Samples: See Sample Information
External Resources: 
References: See references
Population Description: The Keralite people are those from the coastal state of Kerala, in southern India. There are over 31 million Karalites living in Kerala and the surrounding area. They speak the language of Malayalam, which is part of the Dravidian language family. Although there are a variety of religions practiced in the area (including Islam and Christianity), Keralites are predominately Hindu. While tourism is an important part of the local economy, agriculture continues to be an essential part of Kerala. The dominant crops include spices, natural rubber, coconut and rice.


References:


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Ezhavas

Sample UID: SA001833P

Sample Description:This sample consists of Ezhavas residing in the Kollam district of Kerala state on the south-west coast of India. They speak 'Malayalam', which belongs to the Dravidian family of languages. Ezhavas are the largest single Hindu community of the Kerala state and practice agriculture as their basic occupation.

Number of Chromosomes: 148

Relation to Other Samples:

References:
- Ghosh A, Seshadri M. "Indian ethnic populations characterized by dopamine (D4) receptor VNTR polymorphism". Ann Hum Biol. 32:574-84. (2005) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Nairs

Sample UID: SA001834Q

Sample Description:This sample consists of Nairs residing in the Kollam district of Kerala state on the south-west coast of India. They speak 'Malayalam', which belongs to the Dravidian family of languages. Nairs are the military elite of the land.

Number of Chromosomes: 114

Relation to Other Samples:

References:
- Ghosh A, Seshadri M. "Indian ethnic populations characterized by dopamine (D4) receptor VNTR polymorphism". Ann Hum Biol. 32:574-84. (2005) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Muslim (Kerala)

Sample UID: SA001835R

Sample Description:This sample consists of Muslims residing in the Kollam district of Kerala state on the south-west coast of India. They speak 'Malayalam', which belongs to the Dravidian family of languages. Muslims form a significant religio-ethnic group of the state. Muslims of Kollam district analysed in the present study are largely traders and follow the Shafi school of the Sunni sect of Islam.

Number of Chromosomes: 130

Relation to Other Samples:

References:
- Ghosh A, Seshadri M. "Indian ethnic populations characterized by dopamine (D4) receptor VNTR polymorphism". Ann Hum Biol. 32:574-84. (2005) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Keralite

Sample UID: SA001854S

Sample Description:This sample consists of unrelated immigrants from Kerala, a Southwestern state of India. Samples were collected in and around the Hartford area of Connecticut (USA). Malayalam is the language spoken by these individuals.

Number of Chromosomes: 60

Relation to Other Samples:

References:
- Kenneth K. Kidd et al. "Data unpublished".


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Keralites

Sample UID: SA003935U

Sample Description:This sample consists of unrelated, healthy volunteers from Kerala.

Number of Chromosomes: 362

Relation to Other Samples:

References:
- Krishnakumar D, Gurusamy U, Dhandapani K, Surendiran A, Baghel R, Kukreti R, Gangadhar R, Prayaga U, Manjunath S, Adithan C. "Genetic polymorphisms of drug-metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population". Fundam Clin Pharmacol. (Epub, ahead of print) (2011) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: South Indians, Dravidians

Sample UID: SA003613N

Sample Description:This sample consists of controls from a case-control study conducted at the Amrita Institute of Medical Sciences (AIMS), Kochi,Kerala. All the subjects are from Kerala and belong to the Dravidian ethnicity.

Number of Chromosomes: 2000

Relation to Other Samples:

References:
- Sugunan D, Nair AK, Kumar H, Gopalakrishnapillai A. "A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population". BMC Med Genet. 30:118. (2010) Online citation.


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Keralites

Sample UID: SA003963V

Sample Description:This sample is the subset of the Kidd Lab sample SA001854S.This sample consists of unrelated immigrants from Kerala, a Southwestern state of India. Samples were collected in and around the Hartford area of Connecticut (USA). Malayalam is the language spoken by these individuals.

Number of Chromosomes: 50

Relation to Other Samples: Subset of Sample SA001854S

References:
- Publication pending


Sample Information:

Graph estimated heterozygosities for various sites

Sample Name: Malayalee

Sample UID: SA003505N

Sample Description:This sample consists of Malayalee from Kerala, India.

Number of Chromosomes: 50

Relation to Other Samples:

References:
- Chaubey G, Metspalu M, Choi Y, Mägi R, Romero IG, Soares P, van Oven M, Behar DM, Rootsi S, Hudjashov G, Mallick CB, Karmin M, Nelis M, Parik J, Reddy AG, Metspalu E, van Driem G, Xue Y, Tyler-Smith C, Thangaraj K, Singh L, Remm M, Richards MB, Lahr MM, Kayser M, Villems R, Kivisild T. "Population Genetic Structure in Indian Austroasiatic speakers: The Role of Landscape Barriers and Sex-specific Admixture". Mol Biol Evol. (Epub ,ahead of print) (2010) Online citation.


1Geographic Coordinates represent two opposite corners of a rectangle encompassing the area where the population lives.This data is preliminary and changing.

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© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan