ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.
00ALFRED detailed record information

Polymorphism Information

NameALFRED UIDLocus NameLocus Symbol
D12S1344 dinucleotide STRPSI000796WD12S1344D12S1344
Synonyms: MAPKAPK5 ;
Frequency Display Formats:     
Estimated Heterozygosity: 
External Resources:  Typing Protocol Record  
References: See References
Polymorphism Description:  This STRP located 83 kb downstream of exon 12 Glu487Lys functional variant(UID=SI000734O)of gene ALDH2 consists of the dinucleotide sequence (CA) repeated between 11 and 25 times. By the protocol given, the products (including flanking sequence) of the PCR range in size from 222 bp for a 11-repeat allele to 250 bp for a 25-repeat allele.D12S1344 is known to be located within intron 9 of gene MAPKAPK5.
Alleles:
Allele NameAllele SymbolDescription
2222225'-atcgttttctgggata (CA)11 ttctgtccttctttt-3'
2242245'-atcgttttctgggata (CA)12 ttctgtccttctttt-3'
2262265'-atcgttttctgggata (CA)13 ttctgtccttctttt-3'
2282285'-atcgttttctgggata (CA)14 ttctgtccttctttt-3'
2302305'-atcgttttctgggata (CA)15 ttctgtccttctttt-3'
2322325'-atcgttttctgggata (CA)16 ttctgtccttctttt-3'
2342345'-atcgttttctgggata (CA)17 ttctgtccttctttt-3'
2362365'-atcgttttctgggata (CA)18 ttctgtccttctttt-3'
2382385'-atcgttttctgggata (CA)19 ttctgtccttctttt-3'
2402405'-atcgttttctgggata (CA)20 ttctgtccttctttt-3'
2422425'-atcgttttctgggata (CA)21 ttctgtccttctttt-3'
2442445'-atcgttttctgggata (CA)22 ttctgtccttctttt-3'
2462465'-atcgttttctgggata (CA)23 ttctgtccttctttt-3'
2482485'-atcgttttctgggata (CA)24 ttctgtccttctttt-3'
2502505'-atcgttttctgggata (CA)25 ttctgtccttctttt-3'

References:
- Oota H, Pakstis AJ, Bonne-Tamir B, Goldman D, Grigorenko E, Kajuna SL, Karoma NJ, Kungulilo S, Lu RB, Odunsi K, Okonofua F, Zhukova OV, Kidd JR, Kidd KK. "The evolution and population genetics of the ALDH2 locus: random genetic drift, selection, and low levels of recombination". Ann Hum Genet 68:93-109. (2004) Online citation.

© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan