ALFRED: allele frequency database
      The ALlele FREquency Database   
ALFRED is a resource of gene frequency data on human populations
supported by the Yale Center for Medical Informatics.

Sample Information:

Population NameSample NameALFRED UIDNumber of Chromosomes
HanTaiwanese HanSA000001B100

Relation to Other Samples: 
Estimated heterozygosities for various sites: 
Sample Description: Sample is predominantly males descended from immigrants from the Fujian province at least 400 years ago living around Taipei, Taiwan collected by R-B Lu. The Hokkien, the majority of Taiwan's current inhabitants, are descendants of migrants from the Fukian and Guangdong provinces. They traveled from this area in southern China to Taiwan in large numbers during the late 17th and early 18th centuries. They gradually established themselves as the dominant population. The original Fujian-derived population remains an ethnic and linguistic majority, composing roughly 84% of the population. According to 1993 estimates, the Taiwanese dialect of Chinese is spoken by 67% of the population, compared to 20% for the official Mandarin dialect of the mainlanders. The term Taiwanese (also Min-nan-hua) refers to the Hokkien. Taiwanese is part of the southern Min group of Chinese dialects and closely resembles the Amoy dialect spoken in Fujian and in other parts of southern China.
References:
- Chang FM, Kidd JR, Livak KJ, Pakstis AJ, Kidd KK. "The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus". Hum. Genet. 98:91-101. (1996) Online citation.

- Kang AM, Palmatier MA, Kidd KK. "Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3)". Biological Psychiatry 46:151-60. (1999) Online citation.

- Kidd KK et al. http://info.med.yale.edu/genetics/kkidd/pops.html

- Kidd KK, Morar B, Castiglione CM, Zhao H, Pakstis AJ, Speed WC, Bonne-Tamir B, Lu RB, Goldman D, Lee C, Nam YS, Grandy DK, Jenkins T, Kidd JR. "A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus". Hum. Genet. 103:211-27. (1998) Online citation.

- Osier MV, Pakstis AJ, Kidd JR, Lee JF, Yin SJ, Ko HC, Edenberg HJ, Lu RB, and Kidd KK. "Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism". Am. J. Hum. Genet. 64:1147-1157. (1999) Online citation.

- Palmatier MA, Kang AM, Kidd KK. "Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles". Biol. Psychiatry. 46:557-67. (1999) Online citation.



© 2019 Kenneth K Kidd, Yale University. All rights reserved. The full Copyright Notification is also available.
Originally prototyped by Michael Osier with the aid of Kei Cheung
Upgrades and maintenance since 2002 by Haseena Rajeevan